39397

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprG3-sprA1AS/-
Location 2262341..2262538 Replicon chromosome
Accession NZ_AP024738
Organism Staphylococcus aureus strain 59731

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag OCX20_RS11335 Protein ID WP_001802298.1
Coordinates 2262434..2262538 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 2262341..2262379 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OCX20_RS11310 2258582..2259247 - 666 WP_001024095.1 SDR family oxidoreductase -
OCX20_RS11315 2259399..2259719 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
OCX20_RS11320 2259721..2260701 + 981 WP_000019743.1 CDF family zinc efflux transporter CzrB -
OCX20_RS11325 2260967..2262058 + 1092 WP_000495683.1 hypothetical protein -
OCX20_RS11330 2262321..2262395 + 75 Protein_2193 hypothetical protein -
- 2262341..2262379 + 39 - - Antitoxin
OCX20_RS11335 2262434..2262538 - 105 WP_001802298.1 hypothetical protein Toxin
OCX20_RS11340 2263218..2263376 + 159 WP_001792784.1 hypothetical protein -
OCX20_RS11345 2264035..2264892 - 858 WP_000370917.1 HAD family hydrolase -
OCX20_RS11350 2264960..2265742 - 783 WP_000908178.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T39397 WP_001802298.1 NZ_AP024738:c2262538-2262434 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T39397 NZ_AP024738:c2262538-2262434 [Staphylococcus aureus]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTGATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin


Download         Length: 39 bp

>AT39397 NZ_AP024738:2262341-2262379 [Staphylococcus aureus]
AACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTGAC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References