Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprA1-sprA1AS/-
Location 1928323..1928505 Replicon chromosome
Accession NZ_AP024738
Organism Staphylococcus aureus strain 59731

Toxin (Protein)


Gene name sprA1 Uniprot ID -
Locus tag OCX20_RS09400 Protein ID WP_001801861.1
Coordinates 1928323..1928418 (+) Length 32 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 1928446..1928505 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OCX20_RS09365 1923993..1924619 + 627 WP_000669017.1 hypothetical protein -
OCX20_RS09370 1924660..1925001 + 342 WP_000627541.1 DUF3969 family protein -
OCX20_RS09375 1925102..1925674 + 573 WP_000414202.1 hypothetical protein -
OCX20_RS09380 1925872..1926500 - 629 Protein_1847 ImmA/IrrE family metallo-endopeptidase -
OCX20_RS09385 1926803..1926979 - 177 WP_000375477.1 hypothetical protein -
OCX20_RS09390 1926990..1927373 - 384 Protein_1849 hypothetical protein -
OCX20_RS09395 1927977..1928120 - 144 WP_001549059.1 transposase -
OCX20_RS09400 1928323..1928418 + 96 WP_001801861.1 type I toxin-antitoxin system Fst family toxin PepA1 Toxin
- 1928446..1928505 - 60 - - Antitoxin
OCX20_RS09405 1928541..1928642 + 102 WP_001791893.1 hypothetical protein -
OCX20_RS09410 1928620..1928796 - 177 Protein_1853 transposase -
OCX20_RS09415 1928990..1929367 - 378 WP_001037045.1 DUF1433 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 1921642..1947025 25383


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 32 a.a.        Molecular weight: 3554.32 Da        Isoelectric Point: 10.4449

>T39387 WP_001801861.1 NZ_AP024738:1928323-1928418 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Download         Length: 96 bp

>T39387 NZ_AP024738:1928323-1928418 [Staphylococcus aureus]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin


Download         Length: 60 bp

>AT39387 NZ_AP024738:c1928505-1928446 [Staphylococcus aureus]
ACAACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References