Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 2528351..2528535 Replicon chromosome
Accession NZ_AP024736
Organism Staphylococcus aureus strain 59709

Toxin (Protein)


Gene name SprA2 Uniprot ID A0A2P7CQJ7
Locus tag OCX48_RS12745 Protein ID WP_000482647.1
Coordinates 2528428..2528535 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 2528351..2528411 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OCX48_RS12730 2523825..2523992 - 168 WP_001790576.1 hypothetical protein -
OCX48_RS12735 2524223..2525956 - 1734 WP_000486494.1 ABC transporter ATP-binding protein -
OCX48_RS12740 2525981..2527744 - 1764 WP_001064816.1 ABC transporter ATP-binding protein -
- 2528351..2528411 + 61 - - Antitoxin
OCX48_RS12745 2528428..2528535 - 108 WP_000482647.1 type I toxin-antitoxin system Fst family toxin Toxin
OCX48_RS12750 2528669..2529055 - 387 WP_000779360.1 flippase GtxA -
OCX48_RS12755 2529313..2530455 + 1143 WP_001176871.1 glycerate kinase -
OCX48_RS12760 2530515..2531174 + 660 WP_000831301.1 membrane protein -
OCX48_RS12765 2531356..2532567 + 1212 WP_001192075.1 multidrug effflux MFS transporter -
OCX48_RS12770 2532690..2533163 - 474 WP_000456497.1 GyrI-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4012.76 Da        Isoelectric Point: 10.4935

>T39379 WP_000482647.1 NZ_AP024736:c2528535-2528428 [Staphylococcus aureus]
MFNLLIDIMTSALSGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

>T39379 NZ_AP024736:c2528535-2528428 [Staphylococcus aureus]
ATGTTCAATTTATTAATTGACATCATGACTTCAGCTTTAAGCGGCTGTCTTGTTGCGTTTTTTGCACATTGGTTACGAAC
GCGCAACAATAAAAAAGGTGACAAATAA

Antitoxin


Download         Length: 61 bp

>AT39379 NZ_AP024736:2528351-2528411 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2P7CQJ7

Antitoxin

Download structure file

References