39357

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprG3-sprA1AS/-
Location 2272168..2272365 Replicon chromosome
Accession NZ_AP024734
Organism Staphylococcus aureus strain 59691

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag OCX19_RS11440 Protein ID WP_001802298.1
Coordinates 2272261..2272365 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 2272168..2272206 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OCX19_RS11415 2268409..2269074 - 666 WP_261921434.1 SDR family oxidoreductase -
OCX19_RS11420 2269226..2269546 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
OCX19_RS11425 2269548..2270528 + 981 WP_000019743.1 CDF family zinc efflux transporter CzrB -
OCX19_RS11430 2270794..2271885 + 1092 WP_000495683.1 hypothetical protein -
OCX19_RS11435 2272148..2272222 + 75 Protein_2213 hypothetical protein -
- 2272168..2272206 + 39 - - Antitoxin
OCX19_RS11440 2272261..2272365 - 105 WP_001802298.1 hypothetical protein Toxin
OCX19_RS11445 2273045..2273203 + 159 WP_001792784.1 hypothetical protein -
OCX19_RS11450 2273862..2274719 - 858 WP_000370917.1 HAD family hydrolase -
OCX19_RS11455 2274787..2275569 - 783 WP_000908178.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T39357 WP_001802298.1 NZ_AP024734:c2272365-2272261 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T39357 NZ_AP024734:c2272365-2272261 [Staphylococcus aureus]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTGATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin


Download         Length: 39 bp

>AT39357 NZ_AP024734:2272168-2272206 [Staphylococcus aureus]
AACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTGAC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References