39339

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 2489263..2489447 Replicon chromosome
Accession NZ_AP024732
Organism Staphylococcus aureus strain 59621

Toxin (Protein)


Gene name SprA2 Uniprot ID A0A2P7CQJ7
Locus tag OCX17_RS12475 Protein ID WP_000482647.1
Coordinates 2489340..2489447 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 2489263..2489323 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OCX17_RS12460 2484737..2484904 - 168 WP_001790576.1 hypothetical protein -
OCX17_RS12465 2485135..2486868 - 1734 WP_000486494.1 ABC transporter ATP-binding protein -
OCX17_RS12470 2486893..2488656 - 1764 WP_001064816.1 ABC transporter ATP-binding protein -
- 2489263..2489323 + 61 - - Antitoxin
OCX17_RS12475 2489340..2489447 - 108 WP_000482647.1 type I toxin-antitoxin system Fst family toxin Toxin
OCX17_RS12480 2489581..2489967 - 387 WP_000779360.1 flippase GtxA -
OCX17_RS12485 2490225..2491367 + 1143 WP_001176871.1 glycerate kinase -
OCX17_RS12490 2491427..2492086 + 660 WP_000831301.1 membrane protein -
OCX17_RS12495 2492268..2493479 + 1212 WP_001192075.1 multidrug effflux MFS transporter -
OCX17_RS12500 2493602..2494075 - 474 WP_000456497.1 GyrI-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4012.76 Da        Isoelectric Point: 10.4935

>T39339 WP_000482647.1 NZ_AP024732:c2489447-2489340 [Staphylococcus aureus]
MFNLLIDIMTSALSGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

>T39339 NZ_AP024732:c2489447-2489340 [Staphylococcus aureus]
ATGTTCAATTTATTAATTGACATCATGACTTCAGCTTTAAGCGGCTGTCTTGTTGCGTTTTTTGCACATTGGTTACGAAC
GCGCAACAATAAAAAAGGTGACAAATAA

Antitoxin


Download         Length: 61 bp

>AT39339 NZ_AP024732:2489263-2489323 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2P7CQJ7

Antitoxin

Download structure file

References