Detailed information of TA system TA039327

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprA1-sprA1AS/-
• Location: 1879447..1879629
• Replicon: chromosome
• Accession: NZ_AP024732
• Organism: Staphylococcus aureus strain 59621

Toxin (Protein)

• Gene name: sprA1
• Uniprot ID: -
• Locus tag: OCX17_RS09095
• Protein ID: WP_001801861.1
• Coordinates: 1879447..1879542 (+)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	1879570..1879629 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
OCX17_RS09060	1875117..1875743	+	627	WP_000669017.1	hypothetical protein	-
OCX17_RS09065	1875784..1876125	+	342	WP_000627541.1	DUF3969 family protein	-
OCX17_RS09070	1876226..1876798	+	573	WP_000414202.1	hypothetical protein	-
OCX17_RS09075	1876996..1877624	-	629	Protein_1785	ImmA/IrrE family metallo-endopeptidase	-
OCX17_RS09080	1877927..1878103	-	177	WP_000375477.1	hypothetical protein	-
OCX17_RS09085	1878114..1878497	-	384	Protein_1787	hypothetical protein	-
OCX17_RS09090	1879101..1879244	-	144	WP_001549059.1	transposase	-
OCX17_RS09095	1879447..1879542	+	96	WP_001801861.1	type I toxin-antitoxin system Fst family toxin PepA1	Toxin
-	1879570..1879629	-	60	-	-	Antitoxin
OCX17_RS09100	1879665..1879766	+	102	WP_001791893.1	hypothetical protein	-
OCX17_RS09105	1879744..1879920	-	177	Protein_1791	transposase	-
OCX17_RS09110	1880114..1880491	-	378	WP_001037045.1	DUF1433 domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	-	1872766..1898149	25383

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3554.32 Da
• Isoelectric Point: 10.4449

>T39327 WP_001801861.1 NZ_AP024732:1879447-1879542 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Nucleotide

• Length: 96 bp

>T39327 NZ_AP024732:1879447-1879542 [Staphylococcus aureus]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin

Nucleotide

• Length: 60 bp

>AT39327 NZ_AP024732:c1879629-1879570 [Staphylococcus aureus]
ACAACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin