Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2255879..2256095 Replicon chromosome
Accession NZ_AP024730
Organism Staphylococcus aureus strain 59574

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag OCX16_RS11310 Protein ID WP_001802298.1
Coordinates 2255991..2256095 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF1
Locus tag -
Coordinates 2255879..2255934 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OCX16_RS11285 2252139..2252804 - 666 WP_001024095.1 SDR family oxidoreductase -
OCX16_RS11290 2252956..2253276 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
OCX16_RS11295 2253278..2254258 + 981 WP_000019743.1 CDF family zinc efflux transporter CzrB -
OCX16_RS11300 2254524..2255615 + 1092 WP_000495683.1 hypothetical protein -
- 2255879..2255934 + 56 - - Antitoxin
OCX16_RS11310 2255991..2256095 - 105 WP_001802298.1 hypothetical protein Toxin
OCX16_RS11315 2256775..2256933 + 159 WP_001792784.1 hypothetical protein -
OCX16_RS11320 2257592..2258449 - 858 WP_000370917.1 HAD family hydrolase -
OCX16_RS11325 2258517..2259299 - 783 WP_000908178.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T39319 WP_001802298.1 NZ_AP024730:c2256095-2255991 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T39319 NZ_AP024730:c2256095-2255991 [Staphylococcus aureus]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTGATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin


Download         Length: 56 bp

>AT39319 NZ_AP024730:2255879-2255934 [Staphylococcus aureus]
AAAAAGGGCAACACTCGGAAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References