Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprA1-sprA1AS/-
Location 1924963..1925145 Replicon chromosome
Accession NZ_AP024730
Organism Staphylococcus aureus strain 59574

Toxin (Protein)


Gene name sprA1 Uniprot ID -
Locus tag OCX16_RS09385 Protein ID WP_001801861.1
Coordinates 1924963..1925058 (+) Length 32 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 1925086..1925145 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OCX16_RS09350 1920633..1921259 + 627 WP_000669017.1 hypothetical protein -
OCX16_RS09355 1921300..1921641 + 342 WP_000627541.1 DUF3969 family protein -
OCX16_RS09360 1921742..1922314 + 573 WP_000414202.1 hypothetical protein -
OCX16_RS09365 1922512..1923140 - 629 Protein_1843 ImmA/IrrE family metallo-endopeptidase -
OCX16_RS09370 1923443..1923619 - 177 WP_000375477.1 hypothetical protein -
OCX16_RS09375 1923630..1924013 - 384 Protein_1845 hypothetical protein -
OCX16_RS09380 1924617..1924760 - 144 WP_001549059.1 transposase -
OCX16_RS09385 1924963..1925058 + 96 WP_001801861.1 type I toxin-antitoxin system Fst family toxin PepA1 Toxin
- 1925086..1925145 - 60 - - Antitoxin
OCX16_RS09390 1925181..1925282 + 102 WP_001791893.1 hypothetical protein -
OCX16_RS09395 1925260..1925436 - 177 Protein_1849 transposase -
OCX16_RS09400 1925630..1926007 - 378 WP_001037045.1 DUF1433 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 32 a.a.        Molecular weight: 3554.32 Da        Isoelectric Point: 10.4449

>T39311 WP_001801861.1 NZ_AP024730:1924963-1925058 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Download         Length: 96 bp

>T39311 NZ_AP024730:1924963-1925058 [Staphylococcus aureus]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin


Download         Length: 60 bp

>AT39311 NZ_AP024730:c1925145-1925086 [Staphylococcus aureus]
ACAACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References