Detailed information of TA system TA039291

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprA1-sprA1AS/-
• Location: 1884014..1884196
• Replicon: chromosome
• Accession: NZ_AP024728
• Organism: Staphylococcus aureus strain 59553

Toxin (Protein)

• Gene name: sprA1
• Uniprot ID: -
• Locus tag: OCX18_RS09090
• Protein ID: WP_001801861.1
• Coordinates: 1884014..1884109 (+)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	1884137..1884196 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
OCX18_RS09055	1879684..1880310	+	627	WP_000669017.1	hypothetical protein	-
OCX18_RS09060	1880351..1880692	+	342	WP_000627541.1	DUF3969 family protein	-
OCX18_RS09065	1880793..1881365	+	573	WP_000414202.1	hypothetical protein	-
OCX18_RS09070	1881563..1882191	-	629	Protein_1784	ImmA/IrrE family metallo-endopeptidase	-
OCX18_RS09075	1882494..1882670	-	177	WP_000375477.1	hypothetical protein	-
OCX18_RS09080	1882681..1883064	-	384	Protein_1786	hypothetical protein	-
OCX18_RS09085	1883668..1883811	-	144	WP_001549059.1	transposase	-
OCX18_RS09090	1884014..1884109	+	96	WP_001801861.1	type I toxin-antitoxin system Fst family toxin PepA1	Toxin
-	1884137..1884196	-	60	-	-	Antitoxin
OCX18_RS09095	1884232..1884333	+	102	WP_001791893.1	hypothetical protein	-
OCX18_RS09100	1884311..1884487	-	177	Protein_1790	transposase	-
OCX18_RS09105	1884681..1885058	-	378	WP_001037045.1	DUF1433 domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Type I toxin-antitoxin system, toxin Ldr (1-35)

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3554.32 Da
• Isoelectric Point: 10.4449

>T39291 WP_001801861.1 NZ_AP024728:1884014-1884109 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Nucleotide

• Length: 96 bp

>T39291 NZ_AP024728:1884014-1884109 [Staphylococcus aureus]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin

Nucleotide

• Length: 60 bp

>AT39291 NZ_AP024728:c1884196-1884137 [Staphylococcus aureus]
ACAACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin