Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2242263..2242479 Replicon chromosome
Accession NZ_AP024726
Organism Staphylococcus aureus strain 59482

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag OCX11_RS11260 Protein ID WP_001802298.1
Coordinates 2242375..2242479 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF1
Locus tag -
Coordinates 2242263..2242318 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OCX11_RS11230 2237486..2238311 - 826 Protein_2172 class I mannose-6-phosphate isomerase -
OCX11_RS11235 2238523..2239188 - 666 WP_001024095.1 SDR family oxidoreductase -
OCX11_RS11240 2239340..2239660 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
OCX11_RS11245 2239662..2240642 + 981 WP_000019743.1 CDF family zinc efflux transporter CzrB -
OCX11_RS11250 2240908..2241999 + 1092 WP_000495683.1 hypothetical protein -
- 2242263..2242318 + 56 - - Antitoxin
OCX11_RS11260 2242375..2242479 - 105 WP_001802298.1 hypothetical protein Toxin
OCX11_RS11265 2243159..2243317 + 159 WP_001792784.1 hypothetical protein -
OCX11_RS11270 2243976..2244833 - 858 WP_000370917.1 HAD family hydrolase -
OCX11_RS11275 2244901..2245683 - 783 WP_000908178.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T39284 WP_001802298.1 NZ_AP024726:c2242479-2242375 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T39284 NZ_AP024726:c2242479-2242375 [Staphylococcus aureus]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTGATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin


Download         Length: 56 bp

>AT39284 NZ_AP024726:2242263-2242318 [Staphylococcus aureus]
AAAAAGGGCAACACTCGGAAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References