Detailed information of TA system TA039276

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprA1-sprA1AS/-
• Location: 1909653..1909835
• Replicon: chromosome
• Accession: NZ_AP024726
• Organism: Staphylococcus aureus strain 59482

Toxin (Protein)

• Gene name: sprA1
• Uniprot ID: -
• Locus tag: OCX11_RS09340
• Protein ID: WP_001801861.1
• Coordinates: 1909653..1909748 (+)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	1909776..1909835 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
OCX11_RS09305	1905323..1905949	+	627	WP_000669017.1	hypothetical protein	-
OCX11_RS09310	1905990..1906331	+	342	WP_000627541.1	DUF3969 family protein	-
OCX11_RS09315	1906432..1907004	+	573	WP_000414202.1	hypothetical protein	-
OCX11_RS09320	1907202..1907830	-	629	Protein_1834	ImmA/IrrE family metallo-endopeptidase	-
OCX11_RS09325	1908133..1908309	-	177	WP_000375477.1	hypothetical protein	-
OCX11_RS09330	1908320..1908703	-	384	Protein_1836	hypothetical protein	-
OCX11_RS09335	1909307..1909450	-	144	WP_001549059.1	transposase	-
OCX11_RS09340	1909653..1909748	+	96	WP_001801861.1	type I toxin-antitoxin system Fst family toxin PepA1	Toxin
-	1909776..1909835	-	60	-	-	Antitoxin
OCX11_RS09345	1909871..1909972	+	102	WP_001791893.1	hypothetical protein	-
OCX11_RS09350	1909950..1910126	-	177	Protein_1840	transposase	-
OCX11_RS09355	1910320..1910697	-	378	WP_001037045.1	DUF1433 domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	-	1902972..1928355	25383

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3554.32 Da
• Isoelectric Point: 10.4449

>T39276 WP_001801861.1 NZ_AP024726:1909653-1909748 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Nucleotide

• Length: 96 bp

>T39276 NZ_AP024726:1909653-1909748 [Staphylococcus aureus]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin

Nucleotide

• Length: 60 bp

>AT39276 NZ_AP024726:c1909835-1909776 [Staphylococcus aureus]
ACAACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin