Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 2534674..2534858 Replicon chromosome
Accession NZ_AP024723
Organism Staphylococcus aureus strain 59458

Toxin (Protein)


Gene name SprA2 Uniprot ID A0A2P7CQJ7
Locus tag OCX22_RS12775 Protein ID WP_000482647.1
Coordinates 2534751..2534858 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 2534674..2534734 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OCX22_RS12760 2530148..2530315 - 168 WP_001790576.1 hypothetical protein -
OCX22_RS12765 2530546..2532279 - 1734 WP_000486494.1 ABC transporter ATP-binding protein -
OCX22_RS12770 2532304..2534067 - 1764 WP_261921379.1 ABC transporter ATP-binding protein -
- 2534674..2534734 + 61 - - Antitoxin
OCX22_RS12775 2534751..2534858 - 108 WP_000482647.1 type I toxin-antitoxin system Fst family toxin Toxin
OCX22_RS12780 2534992..2535378 - 387 WP_000779360.1 flippase GtxA -
OCX22_RS12785 2535636..2536778 + 1143 WP_001176871.1 glycerate kinase -
OCX22_RS12790 2536838..2537497 + 660 WP_000831301.1 membrane protein -
OCX22_RS12795 2537679..2538890 + 1212 WP_001192075.1 multidrug effflux MFS transporter -
OCX22_RS12800 2539013..2539486 - 474 WP_000456497.1 GyrI-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4012.76 Da        Isoelectric Point: 10.4935

>T39268 WP_000482647.1 NZ_AP024723:c2534858-2534751 [Staphylococcus aureus]
MFNLLIDIMTSALSGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

>T39268 NZ_AP024723:c2534858-2534751 [Staphylococcus aureus]
ATGTTCAATTTATTAATTGACATCATGACTTCAGCTTTAAGCGGCTGTCTTGTTGCGTTTTTTGCACATTGGTTACGAAC
GCGCAACAATAAAAAAGGTGACAAATAA

Antitoxin


Download         Length: 61 bp

>AT39268 NZ_AP024723:2534674-2534734 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2P7CQJ7

Antitoxin

Download structure file

References