Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2258359..2258575 Replicon chromosome
Accession NZ_AP024723
Organism Staphylococcus aureus strain 59458

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag OCX22_RS11320 Protein ID WP_001802298.1
Coordinates 2258471..2258575 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF1
Locus tag -
Coordinates 2258359..2258414 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OCX22_RS11295 2254619..2255284 - 666 WP_001024095.1 SDR family oxidoreductase -
OCX22_RS11300 2255436..2255756 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
OCX22_RS11305 2255758..2256738 + 981 WP_000019743.1 CDF family zinc efflux transporter CzrB -
OCX22_RS11310 2257004..2258095 + 1092 WP_000495683.1 hypothetical protein -
- 2258359..2258414 + 56 - - Antitoxin
OCX22_RS11320 2258471..2258575 - 105 WP_001802298.1 hypothetical protein Toxin
OCX22_RS11325 2259255..2259413 + 159 WP_001792784.1 hypothetical protein -
OCX22_RS11330 2260072..2260929 - 858 WP_261921371.1 HAD family hydrolase -
OCX22_RS11335 2260997..2261779 - 783 WP_000908178.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T39264 WP_001802298.1 NZ_AP024723:c2258575-2258471 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T39264 NZ_AP024723:c2258575-2258471 [Staphylococcus aureus]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTGATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin


Download         Length: 56 bp

>AT39264 NZ_AP024723:2258359-2258414 [Staphylococcus aureus]
AAAAAGGGCAACACTCGGAAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References