Detailed information of TA system TA039124

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): bsrE-as-bsrE/-
• Location: 2041663..2041909
• Replicon: chromosome
• Accession: NZ_AP024628
• Organism: Bacillus subtilis strain BEST3145

Toxin (Protein)

• Gene name: bsrE
• Uniprot ID: -
• Locus tag: K6K00_RS10100
• Protein ID: WP_109789044.1
• Coordinates: 2041663..2041755 (+)
• Length: 31 a.a.

Antitoxin (RNA)

Gene name	as-bsrE
Locus tag	-
Coordinates	2041736..2041909 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
K6K00_RS10085	2036822..2037157	+	336	WP_009967409.1	hypothetical protein	-
K6K00_RS10090	2037204..2040809	-	3606	WP_004399367.1	P-loop NTPase fold protein	-
K6K00_RS10095	2041042..2041374	-	333	WP_026009814.1	hypothetical protein	-
K6K00_RS10100	2041663..2041755	+	93	WP_109789044.1	type I toxin-antitoxin system toxin BsrE	Toxin
-	2041736..2041909	-	174	-	-	Antitoxin
K6K00_RS10105	2042024..2042866	-	843	WP_003231327.1	hypothetical protein	-
K6K00_RS10110	2043066..2043524	-	459	WP_003231326.1	type VII secretion system immunity protein YobK	-
K6K00_RS10115	2043534..2045336	-	1803	WP_004399481.1	LXG family T7SS effector ribonuclease toxin YobL	-
K6K00_RS10120	2045438..2045995	-	558	WP_004399321.1	SMI1/KNR4 family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	-	2027648..2051326	23678

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (1-24)

Sequences

Toxin

Protein

• Length: 31 a.a.
• Molecular weight: 3358.16 Da
• Isoelectric Point: 4.1840

>T39124 WP_109789044.1 NZ_AP024628:2041663-2041755 [Bacillus subtilis]
MSTFQALMLMLAIGSFIIALLTYIEKIDLP

Nucleotide

• Length: 93 bp

>T39124 NZ_AP024628:2041663-2041755 [Bacillus subtilis]
ATGTCAACATTCCAGGCATTAATGCTAATGCTTGCAATCGGGTCGTTTATAATCGCCCTATTGACGTATATAGAAAAAAT
AGACCTCCCTTGA

Antitoxin

Nucleotide

• Length: 174 bp

>AT39124 NZ_AP024628:c2041909-2041736 [Bacillus subtilis]
TTACAATACATTACAGTGCATTTCTTTAATGAGAAATGCATAAAATAAAAAAGACCGAGGTGCTACCAACACCCCGGCTC
TGTACAAAAAGTTGCCCATCAAAGGGCTTGCTCGATGTGGTTCTAGGTAGGCCTATCCCTTCAGGTTCTGAGGCTCAAGG
GAGGTCTATTTTTT

Structures

Antitoxin