Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) bsrE-as-bsrE/-
Location 2035719..2035965 Replicon chromosome
Accession NZ_AP024626
Organism Bacillus subtilis strain BEST3125

Toxin (Protein)


Gene name bsrE Uniprot ID -
Locus tag K6K02_RS10115 Protein ID WP_109789044.1
Coordinates 2035719..2035811 (+) Length 31 a.a.

Antitoxin (RNA)


Gene name as-bsrE
Locus tag -
Coordinates 2035792..2035965 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
K6K02_RS10100 2030878..2031213 + 336 WP_009967409.1 hypothetical protein -
K6K02_RS10105 2031260..2034865 - 3606 WP_004399367.1 P-loop NTPase fold protein -
K6K02_RS10110 2035098..2035430 - 333 WP_026009814.1 hypothetical protein -
K6K02_RS10115 2035719..2035811 + 93 WP_109789044.1 type I toxin-antitoxin system toxin BsrE Toxin
- 2035792..2035965 - 174 - - Antitoxin
K6K02_RS10120 2036080..2036922 - 843 WP_003231327.1 hypothetical protein -
K6K02_RS10125 2037122..2037580 - 459 WP_003231326.1 type VII secretion system immunity protein YobK -
K6K02_RS10130 2037590..2039392 - 1803 WP_004399481.1 LXG family T7SS effector ribonuclease toxin YobL -
K6K02_RS10135 2039494..2040051 - 558 WP_004399321.1 SMI1/KNR4 family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 2022114..2045382 23268


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Small toxic protein BsrE-like

(1-24)


Sequences

Toxin        


Download         Length: 31 a.a.        Molecular weight: 3358.16 Da        Isoelectric Point: 4.1840

>T39078 WP_109789044.1 NZ_AP024626:2035719-2035811 [Bacillus subtilis]
MSTFQALMLMLAIGSFIIALLTYIEKIDLP

Download         Length: 93 bp

>T39078 NZ_AP024626:2035719-2035811 [Bacillus subtilis]
ATGTCAACATTCCAGGCATTAATGCTAATGCTTGCAATCGGGTCGTTTATAATCGCCCTATTGACGTATATAGAAAAAAT
AGACCTCCCTTGA

Antitoxin


Download         Length: 174 bp

>AT39078 NZ_AP024626:c2035965-2035792 [Bacillus subtilis]
TTACAATACATTACAGTGCATTTCTTTAATGAGAAATGCATAAAATAAAAAAGACCGAGGTGCTACCAACACCCCGGCTC
TGTACAAAAAGTTGCCCATCAAAGGGCTTGCTCGATGTGGTTCTAGGTAGGCCTATCCCTTCAGGTTCTGAGGCTCAAGG
GAGGTCTATTTTTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References