Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type I Classification (family/domain) bsrE-as-bsrE/-
Location 2035981..2036227 Replicon chromosome
Accession NZ_AP024625
Organism Bacillus subtilis strain BEST3109

Toxin (Protein)


Gene name bsrE Uniprot ID -
Locus tag BsBEST3145_RS10135 Protein ID WP_109789044.1
Coordinates 2035981..2036073 (+) Length 31 a.a.

Antitoxin (RNA)


Gene name as-bsrE
Locus tag -
Coordinates 2036054..2036227 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BsBEST3145_RS10120 2031140..2031475 + 336 WP_009967409.1 hypothetical protein -
BsBEST3145_RS10125 2031522..2035127 - 3606 WP_004399367.1 P-loop NTPase fold protein -
BsBEST3145_RS10130 2035360..2035692 - 333 WP_026009814.1 hypothetical protein -
BsBEST3145_RS10135 2035981..2036073 + 93 WP_109789044.1 type I toxin-antitoxin system toxin BsrE Toxin
- 2036054..2036227 - 174 - - Antitoxin
BsBEST3145_RS10140 2036342..2037184 - 843 WP_003231327.1 hypothetical protein -
BsBEST3145_RS10145 2037384..2037842 - 459 WP_003231326.1 type VII secretion system immunity protein YobK -
BsBEST3145_RS10150 2037852..2039654 - 1803 WP_004399481.1 LXG family T7SS effector ribonuclease toxin YobL -
BsBEST3145_RS10155 2039756..2040313 - 558 WP_004399321.1 SMI1/KNR4 family protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 2022376..2045644 23268


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(1-24)


Sequences


Toxin        


Download         Length: 31 a.a.        Molecular weight: 3358.16 Da        Isoelectric Point: 4.1840

>T39055 WP_109789044.1 NZ_AP024625:2035981-2036073 [Bacillus subtilis]
MSTFQALMLMLAIGSFIIALLTYIEKIDLP

Download         Length: 93 bp

>T39055 NZ_AP024625:2035981-2036073 [Bacillus subtilis]
ATGTCAACATTCCAGGCATTAATGCTAATGCTTGCAATCGGGTCGTTTATAATCGCCCTATTGACGTATATAGAAAAAAT
AGACCTCCCTTGA

Antitoxin


Download         Length: 174 bp

>AT39055 NZ_AP024625:c2036227-2036054 [Bacillus subtilis]
TTACAATACATTACAGTGCATTTCTTTAATGAGAAATGCATAAAATAAAAAAGACCGAGGTGCTACCAACACCCCGGCTC
TGTACAAAAAGTTGCCCATCAAAGGGCTTGCTCGATGTGGTTCTAGGTAGGCCTATCCCTTCAGGTTCTGAGGCTCAAGG
GAGGTCTATTTTTT

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Download structure file

References