Detailed information of TA system TA039055

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): bsrE-as-bsrE/-
• Location: 2035981..2036227
• Replicon: chromosome
• Accession: NZ_AP024625
• Organism: Bacillus subtilis strain BEST3109

Toxin (Protein)

• Gene name: bsrE
• Uniprot ID: -
• Locus tag: BsBEST3145_RS10135
• Protein ID: WP_109789044.1
• Coordinates: 2035981..2036073 (+)
• Length: 31 a.a.

Antitoxin (RNA)

Gene name	as-bsrE
Locus tag	-
Coordinates	2036054..2036227 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
BsBEST3145_RS10120	2031140..2031475	+	336	WP_009967409.1	hypothetical protein	-
BsBEST3145_RS10125	2031522..2035127	-	3606	WP_004399367.1	P-loop NTPase fold protein	-
BsBEST3145_RS10130	2035360..2035692	-	333	WP_026009814.1	hypothetical protein	-
BsBEST3145_RS10135	2035981..2036073	+	93	WP_109789044.1	type I toxin-antitoxin system toxin BsrE	Toxin
-	2036054..2036227	-	174	-	-	Antitoxin
BsBEST3145_RS10140	2036342..2037184	-	843	WP_003231327.1	hypothetical protein	-
BsBEST3145_RS10145	2037384..2037842	-	459	WP_003231326.1	type VII secretion system immunity protein YobK	-
BsBEST3145_RS10150	2037852..2039654	-	1803	WP_004399481.1	LXG family T7SS effector ribonuclease toxin YobL	-
BsBEST3145_RS10155	2039756..2040313	-	558	WP_004399321.1	SMI1/KNR4 family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	-	2022376..2045644	23268

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (1-24)

Sequences

Toxin

Protein

• Length: 31 a.a.
• Molecular weight: 3358.16 Da
• Isoelectric Point: 4.1840

>T39055 WP_109789044.1 NZ_AP024625:2035981-2036073 [Bacillus subtilis]
MSTFQALMLMLAIGSFIIALLTYIEKIDLP

Nucleotide

• Length: 93 bp

>T39055 NZ_AP024625:2035981-2036073 [Bacillus subtilis]
ATGTCAACATTCCAGGCATTAATGCTAATGCTTGCAATCGGGTCGTTTATAATCGCCCTATTGACGTATATAGAAAAAAT
AGACCTCCCTTGA

Antitoxin

Nucleotide

• Length: 174 bp

>AT39055 NZ_AP024625:c2036227-2036054 [Bacillus subtilis]
TTACAATACATTACAGTGCATTTCTTTAATGAGAAATGCATAAAATAAAAAAGACCGAGGTGCTACCAACACCCCGGCTC
TGTACAAAAAGTTGCCCATCAAAGGGCTTGCTCGATGTGGTTCTAGGTAGGCCTATCCCTTCAGGTTCTGAGGCTCAAGG
GAGGTCTATTTTTT

Structures

Antitoxin