Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) bsrE-as-bsrE/-
Location 2038485..2038731 Replicon chromosome
Accession NZ_AP024623
Organism Bacillus subtilis strain BEST3102

Toxin (Protein)


Gene name bsrE Uniprot ID -
Locus tag K6J99_RS10140 Protein ID WP_109789044.1
Coordinates 2038485..2038577 (+) Length 31 a.a.

Antitoxin (RNA)


Gene name as-bsrE
Locus tag -
Coordinates 2038558..2038731 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
K6J99_RS10125 2033644..2033979 + 336 WP_009967409.1 hypothetical protein -
K6J99_RS10130 2034026..2037631 - 3606 WP_004399367.1 P-loop NTPase fold protein -
K6J99_RS10135 2037864..2038196 - 333 WP_026009814.1 hypothetical protein -
K6J99_RS10140 2038485..2038577 + 93 WP_109789044.1 type I toxin-antitoxin system toxin BsrE Toxin
- 2038558..2038731 - 174 - - Antitoxin
K6J99_RS10145 2038846..2039688 - 843 WP_003231327.1 hypothetical protein -
K6J99_RS10150 2039888..2040346 - 459 WP_003231326.1 type VII secretion system immunity protein YobK -
K6J99_RS10155 2040356..2042158 - 1803 WP_004399481.1 LXG family T7SS effector ribonuclease toxin YobL -
K6J99_RS10160 2042260..2042817 - 558 WP_004399321.1 SMI1/KNR4 family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 2014531..2047228 32697


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Small toxic protein BsrE-like

(1-24)


Sequences

Toxin        


Download         Length: 31 a.a.        Molecular weight: 3358.16 Da        Isoelectric Point: 4.1840

>T39009 WP_109789044.1 NZ_AP024623:2038485-2038577 [Bacillus subtilis]
MSTFQALMLMLAIGSFIIALLTYIEKIDLP

Download         Length: 93 bp

>T39009 NZ_AP024623:2038485-2038577 [Bacillus subtilis]
ATGTCAACATTCCAGGCATTAATGCTAATGCTTGCAATCGGGTCGTTTATAATCGCCCTATTGACGTATATAGAAAAAAT
AGACCTCCCTTGA

Antitoxin


Download         Length: 174 bp

>AT39009 NZ_AP024623:c2038731-2038558 [Bacillus subtilis]
TTACAATACATTACAGTGCATTTCTTTAATGAGAAATGCATAAAATAAAAAAGACCGAGGTGCTACCAACACCCCGGCTC
TGTACAAAAAGTTGCCCATCAAAGGGCTTGCTCGATGTGGTTCTAGGTAGGCCTATCCCTTCAGGTTCTGAGGCTCAAGG
GAGGTCTATTTTTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References