Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2737264..2737526 Replicon chromosome
Accession NZ_AP024511
Organism Staphylococcus aureus isolate 2007-13

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag KJS82_RS13535 Protein ID WP_001802298.1
Coordinates 2737264..2737368 (+) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF2
Locus tag -
Coordinates 2737363..2737526 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KJS82_RS13520 2734061..2734843 + 783 WP_000908182.1 ABC transporter ATP-binding protein -
KJS82_RS13525 2734911..2735768 + 858 WP_000370925.1 Cof-type HAD-IIB family hydrolase -
KJS82_RS13530 2736426..2736584 - 159 WP_001792784.1 hypothetical protein -
KJS82_RS13535 2737264..2737368 + 105 WP_001802298.1 hypothetical protein Toxin
- 2737363..2737526 - 164 - - Antitoxin
KJS82_RS13540 2737801..2738892 - 1092 WP_000495669.1 hypothetical protein -
KJS82_RS13545 2739158..2740135 - 978 WP_000019734.1 CDF family zinc efflux transporter CzrB -
KJS82_RS13550 2740137..2740457 - 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
KJS82_RS13555 2740609..2741274 + 666 WP_001024095.1 SDR family oxidoreductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T38533 WP_001802298.1 NZ_AP024511:2737264-2737368 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T38533 NZ_AP024511:2737264-2737368 [Staphylococcus aureus]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTGATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin


Download         Length: 164 bp

>AT38533 NZ_AP024511:c2737526-2737363 [Staphylococcus aureus]
GTAGTAAGTAGAAGCAAAAGATGAAAATCTTTAACTCTTGAAACACAAAAAGGGCAACACTCGGAAACATGTTACCCTAA
TGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAATGCCGGTCAAAGCGAATAGAAGGTT
ATTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References