Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/RelE-HTH
Location 1024449..1025055 Replicon chromosome
Accession NZ_AP024469
Organism Geobacter sp. SVR

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag GSVR_RS04815 Protein ID WP_173195985.1
Coordinates 1024732..1025055 (-) Length 108 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag GSVR_RS04810 Protein ID WP_173195987.1
Coordinates 1024449..1024739 (-) Length 97 a.a.

Genomic Context

GSVR_RS04790GSVR_RS04805GSVR_RS04795GSVR_RS04800GSVR_RS04810GSVR_RS04815GSVR_RS04820GSVR_RS04825GSVR_RS04830GSVR_RS04835
Location: 1021604..1021909 (306 bp)
Type: Others
Protein ID: WP_173195995.1
Location: 1023565..1024413 (849 bp)
Type: Others
Protein ID: WP_173195989.1
Location: 1021998..1022618 (621 bp)
Type: Others
Protein ID: WP_173195993.1
Location: 1023111..1023317 (207 bp)
Type: Others
Protein ID: WP_173195991.1
Location: 1024449..1024739 (291 bp)
Type: Antitoxin
Protein ID: WP_173195987.1
Location: 1024732..1025055 (324 bp)
Type: Toxin
Protein ID: WP_173195985.1
Location: 1025115..1026440 (1326 bp)
Type: Others
Protein ID: WP_173195983.1
Location: 1026641..1028245 (1605 bp)
Type: Others
Protein ID: WP_173195981.1
Location: 1028242..1028427 (186 bp)
Type: Others
Protein ID: WP_173195979.1
Location: 1029347..1029622 (276 bp)
Type: Others
Protein ID: WP_173195977.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
GSVR_RS047901021604..1021909+306WP_173195995.1hypothetical protein-
GSVR_RS047951021998..1022618-621WP_173195993.1hypothetical protein-
GSVR_RS048001023111..1023317-207WP_173195991.1AlpA family phage regulatory protein-
GSVR_RS048051023565..1024413+849WP_173195989.1winged helix-turn-helix domain-containing protein-
GSVR_RS048101024449..1024739-291WP_173195987.1helix-turn-helix domain-containing proteinAntitoxin
GSVR_RS048151024732..1025055-324WP_173195985.1type II toxin-antitoxin system RelE/ParE family toxinToxin
GSVR_RS048201025115..1026440-1326WP_173195983.1site-specific integrase-
GSVR_RS048251026641..1028245-1605WP_173195981.1recombinase family protein-
GSVR_RS048301028242..1028427-186WP_173195979.1hypothetical protein-
GSVR_RS048351029347..1029622-276WP_173195977.1hypothetical protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
-insideGenomic island--999032..104968350651


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-2

(42-103)

Antitoxin

Cro/C1-type helix-turn-helix domain

(37-88)


Sequences

Toxin        


Download         Length: 108 a.a.        Molecular weight: 12150.18 Da        Isoelectric Point: 9.6573

>T38464 WP_173195985.1 NZ_AP024469:c1025055-1024732 [Geobacter sp. SVR]
MEFIETPVFTKLIATMLPDDDYRLLQDDIAKNPQLGDLIQGGGGIRKLRFALPGTGKRGGARLIYYWQTSRDKIYMLLAY
AKAKKENLEPEQVAILKSLVKELERHG

Download         Length: 324 bp

>T38464 NZ_AP024469:c1025055-1024732 [Geobacter sp. SVR]
ATGGAATTTATCGAGACCCCAGTATTCACAAAGCTGATAGCAACTATGTTGCCCGATGATGATTACCGCCTTCTCCAAGA
CGATATTGCTAAGAACCCGCAATTAGGCGACTTGATTCAAGGCGGCGGTGGGATTCGTAAGCTTCGCTTCGCGCTGCCCG
GCACGGGCAAGCGGGGCGGTGCCCGCCTCATTTACTATTGGCAGACATCCAGGGATAAAATTTACATGCTGCTGGCATAC
GCCAAGGCAAAGAAAGAGAATCTTGAGCCGGAGCAGGTAGCCATACTCAAGTCATTAGTGAAGGAGTTGGAACGTCATGG
ATAA

Antitoxin


Download         Length: 97 a.a.        Molecular weight: 10642.41 Da        Isoelectric Point: 9.8934

>AT38464 WP_173195987.1 NZ_AP024469:c1024739-1024449 [Geobacter sp. SVR]
MDKELFDQLHKSMKEAVAIAKGEMMPSRVFTVESPDVKAVREKTGLSQAMFAAMIGVKVKTLQNWEQHRRSPTGAAAALL
TIFDREPETAMKALHG

Download         Length: 291 bp

>AT38464 NZ_AP024469:c1024739-1024449 [Geobacter sp. SVR]
ATGGATAAAGAATTATTTGACCAATTACACAAAAGTATGAAAGAAGCCGTTGCGATTGCCAAAGGCGAAATGATGCCATC
AAGAGTATTCACTGTCGAGTCACCTGACGTGAAGGCCGTGCGCGAAAAAACGGGGCTGTCACAAGCCATGTTCGCCGCAA
TGATTGGTGTGAAGGTAAAAACCTTGCAAAATTGGGAGCAGCACCGGCGTAGCCCTACCGGTGCGGCAGCTGCGCTTCTG
ACTATATTTGACCGTGAACCGGAAACTGCTATGAAGGCTCTGCATGGTTAA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
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Antitoxin

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Source
ID
Structure
No matching records found

References