Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) prlF-yhaV (relBE)/YhaV-PrlF
Location 1019944..1020770 Replicon chromosome
Accession NZ_AP024354
Organism Pseudomonas alcaligenes strain KAM426

Toxin (Protein)


Gene name yhaV Uniprot ID -
Locus tag JUH08_RS04755 Protein ID WP_088177213.1
Coordinates 1019944..1020447 (-) Length 168 a.a.

Antitoxin (Protein)


Gene name prlF Uniprot ID -
Locus tag JUH08_RS04760 Protein ID WP_088177212.1
Coordinates 1020444..1020770 (-) Length 109 a.a.

Genomic Context

JUH08_RS04725JUH08_RS04730JUH08_RS04735JUH08_RS04750JUH08_RS04765JUH08_RS04770JUH08_RS04740JUH08_RS04745JUH08_RS04755JUH08_RS04760JUH08_RS04775JUH08_RS04780JUH08_RS04785
Location: 1015978..1016247 (270 bp)
Type: Others
Protein ID: WP_203790994.1
Location: 1016244..1016804 (561 bp)
Type: Others
Protein ID: WP_203790996.1
Location: 1016816..1017978 (1163 bp)
Type: Others
Protein ID: WP_128688142.1
Location: 1019395..1019601 (207 bp)
Type: Others
Protein ID: WP_203791002.1
Location: 1021026..1022351 (1326 bp)
Type: Others
Protein ID: WP_088177214.1
Location: 1022352..1022618 (267 bp)
Type: Others
Protein ID: WP_088177211.1
Location: 1018262..1018822 (561 bp)
Type: Others
Protein ID: WP_203790998.1
Location: 1018908..1019123 (216 bp)
Type: Others
Protein ID: WP_203791000.1
Location: 1019944..1020447 (504 bp)
Type: Toxin
Protein ID: WP_088177213.1
Location: 1020444..1020770 (327 bp)
Type: Antitoxin
Protein ID: WP_088177212.1
Location: 1022666..1022869 (204 bp)
Type: Others
Protein ID: WP_088177210.1
Location: 1022955..1023086 (132 bp)
Type: Others
Protein ID: WP_143492042.1
Location: 1023650..1024630 (981 bp)
Type: Others
Protein ID: Protein_937
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
JUH08_RS047251015978..1016247+270WP_203790994.1hypothetical protein-
JUH08_RS047301016244..1016804+561WP_203790996.1zeta toxin family protein-
JUH08_RS047351016816..1017978+1163WP_128688142.1IS3 family transposase-
JUH08_RS047401018262..1018822-561WP_203790998.1hypothetical protein-
JUH08_RS047451018908..1019123-216WP_203791000.1hypothetical protein-
JUH08_RS047501019395..1019601+207WP_203791002.1hypothetical protein-
JUH08_RS047551019944..1020447-504WP_088177213.1type II toxin-antitoxin system YhaV family toxinToxin
JUH08_RS047601020444..1020770-327WP_088177212.1type II toxin-antitoxin system PrlF family antitoxinAntitoxin
JUH08_RS047651021026..1022351+1326WP_088177214.1HipA domain-containing protein-
JUH08_RS047701022352..1022618+267WP_088177211.1helix-turn-helix domain-containing protein-
JUH08_RS047751022666..1022869-204WP_088177210.1hypothetical protein-
JUH08_RS047801022955..1023086-132WP_143492042.1DUF4113 domain-containing protein-
JUH08_RS047851023650..1024630-981Protein_937IS5-like element ISPa16 family transposase-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
-insideIntegrative and Conjugative Element-xcpA/pilD / pilC / pilB947520..1076676129156


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin endonuclease, YhaV

(16-152)

Antitoxin

PrlF antitoxin

(8-106)


Sequences

Toxin        


Download         Length: 168 a.a.        Molecular weight: 19179.83 Da        Isoelectric Point: 9.9994

>T38428 WP_088177213.1 NZ_AP024354:c1020447-1019944 [Pseudomonas alcaligenes]
MSHDHGKPMVAHGWTVFAHPLFLDQLESLIQKVELSKQKDPVGYRKKNAAKRLAAIAKLAFDVIPQDPSKPEYRQGGTLG
EEHKHWFRAKFFQQYRLFFRYHGPSKIIVLAWVNDDDTKRAYESSDDAYKVFRKMLASGHPPDAWDKLLKEATQENARLN
SAATSVN

Download         Length: 504 bp

>T38428 NZ_AP024354:c1020447-1019944 [Pseudomonas alcaligenes]
ATGAGCCACGACCACGGCAAGCCAATGGTTGCCCATGGCTGGACAGTATTTGCGCACCCCTTGTTTCTGGATCAGCTCGA
AAGCCTCATTCAGAAAGTTGAGCTCTCAAAACAAAAAGACCCCGTGGGCTATCGCAAGAAGAATGCAGCCAAGCGGCTGG
CAGCCATCGCCAAGCTGGCTTTTGACGTTATCCCACAAGACCCGAGCAAGCCCGAATACCGCCAAGGTGGCACATTGGGC
GAGGAACATAAGCACTGGTTCCGTGCCAAGTTTTTTCAGCAGTATCGGCTGTTCTTCCGGTACCACGGCCCAAGCAAGAT
AATCGTCTTGGCGTGGGTTAATGATGACGACACCAAGCGTGCCTATGAGAGCAGCGATGACGCCTACAAGGTGTTTCGAA
AAATGCTCGCGAGCGGACATCCGCCTGACGCGTGGGATAAGCTGCTGAAGGAAGCCACGCAGGAAAACGCACGATTAAAT
TCGGCCGCCACCTCGGTCAACTGA

Antitoxin


Download         Length: 109 a.a.        Molecular weight: 12030.33 Da        Isoelectric Point: 4.5700

>AT38428 WP_088177212.1 NZ_AP024354:c1020770-1020444 [Pseudomonas alcaligenes]
MARALEVESTLTDRYQTTVPETVRRALQLNKRDKIHYSIRPSGEVVLSRAEHSEDDPAIGQFLSFLAHDIAANPQHLQAI
DSNLVARIHSLVDSNEIDLDAPLSADDE

Download         Length: 327 bp

>AT38428 NZ_AP024354:c1020770-1020444 [Pseudomonas alcaligenes]
ATGGCCAGAGCACTCGAAGTCGAATCCACCCTTACCGACCGCTACCAGACGACGGTACCAGAGACTGTTCGCCGCGCACT
TCAGCTAAACAAGCGCGACAAAATTCATTACTCGATTCGCCCCAGCGGTGAGGTCGTACTGAGCCGTGCAGAGCACTCTG
AGGATGACCCGGCAATCGGCCAGTTTCTCAGTTTTCTTGCACATGACATCGCAGCGAACCCTCAGCACCTGCAAGCCATA
GATTCAAATCTCGTGGCACGCATCCACTCGCTGGTCGATAGCAATGAGATAGATCTGGATGCCCCGCTGTCGGCAGACGA
TGAATGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
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Antitoxin

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Source
ID
Structure
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References