38405

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/-
Location 4485977..4486631 Replicon chromosome
Accession NZ_AP024342
Organism Pseudomonas sp. Eqa60

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag KI242_RS20180 Protein ID WP_053152689.1
Coordinates 4485977..4486327 (+) Length 117 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag KI242_RS20185 Protein ID WP_053152691.1
Coordinates 4486314..4486631 (+) Length 106 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KI242_RS20170 (PEQA60_40370) 4482736..4484268 + 1533 WP_019092840.1 NADH-quinone oxidoreductase subunit M -
KI242_RS20175 (PEQA60_40380) 4484276..4485739 + 1464 WP_011062196.1 NADH-quinone oxidoreductase subunit NuoN -
KI242_RS20180 (PEQA60_40390) 4485977..4486327 + 351 WP_053152689.1 hypothetical protein Toxin
KI242_RS20185 (PEQA60_40400) 4486314..4486631 + 318 WP_053152691.1 transcriptional regulator Antitoxin
KI242_RS20190 (PEQA60_40410) 4486700..4488082 - 1383 WP_053159449.1 cysteine--tRNA ligase -
KI242_RS20195 (PEQA60_40420) 4488101..4489801 - 1701 WP_053159451.1 glutamine--tRNA ligase/YqeY domain fusion protein -
KI242_RS20200 (PEQA60_40430) 4490072..4490575 + 504 WP_011062201.1 peptidylprolyl isomerase -
KI242_RS20205 (PEQA60_40440) 4490572..4491324 + 753 WP_011062202.1 UDP-2,3-diacylglucosamine diphosphatase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Cro/C1-type helix-turn-helix domain

(48-101)


Sequences

Toxin        


Download         Length: 117 a.a.        Molecular weight: 13936.07 Da        Isoelectric Point: 9.6226

>T38405 WP_053152689.1 NZ_AP024342:4485977-4486327 [Pseudomonas sp. Eqa60]
MNALFIELPAFARYRKGFLDDELFCELQIELLRHPHAGVLIQGTGGLRKMRFIDERRNKGRRGGLRVIYYWWSGGAQFWL
FTLFDKEQMDDLLPQQRQQLKQLLEREIEARRHDQT

Download         Length: 351 bp

>T38405 NZ_AP024342:4485977-4486327 [Pseudomonas sp. Eqa60]
ATGAATGCTCTGTTTATTGAACTACCGGCATTTGCGCGATACCGAAAGGGCTTCCTTGACGACGAATTGTTCTGCGAACT
GCAGATCGAGTTGCTGCGCCACCCGCACGCGGGCGTTCTGATTCAGGGCACTGGCGGCTTGCGCAAGATGCGTTTCATCG
ATGAGCGACGCAATAAGGGCAGGCGTGGCGGGCTGAGGGTGATTTATTACTGGTGGTCCGGAGGAGCACAGTTCTGGCTC
TTCACCCTGTTCGACAAGGAGCAGATGGACGACCTGCTACCGCAGCAGCGACAACAGCTCAAACAACTGCTGGAACGTGA
AATCGAGGCCAGAAGACATGACCAAACGTGA

Antitoxin


Download         Length: 106 a.a.        Molecular weight: 12050.92 Da        Isoelectric Point: 10.4439

>AT38405 WP_053152691.1 NZ_AP024342:4486314-4486631 [Pseudomonas sp. Eqa60]
MTKRDIFSELVEGIDALTQERQGKITLRSHKVKLDKLPPITAAEVMNIRQQLNLSRSVFAMYLRTNTRTLENWEQGRAIP
NAQATTLIRLVERYPDTVERLASLA

Download         Length: 318 bp

>AT38405 NZ_AP024342:4486314-4486631 [Pseudomonas sp. Eqa60]
ATGACCAAACGTGACATCTTTTCCGAACTGGTTGAAGGCATCGACGCCCTCACCCAGGAACGCCAGGGCAAGATCACCCT
GCGCAGCCATAAAGTGAAACTCGACAAGCTGCCCCCCATCACCGCCGCCGAGGTGATGAACATCCGCCAGCAACTCAACC
TCTCGCGCTCGGTGTTCGCCATGTACCTGCGCACCAACACCCGCACCCTGGAGAACTGGGAACAGGGCCGCGCCATACCC
AACGCCCAGGCCACGACCTTGATACGCCTGGTGGAGCGCTACCCCGATACAGTGGAGCGCCTCGCCTCGCTGGCCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References