Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | higBA (relBE)/MqsA(antitoxin) |
Location | 4294025..4294682 | Replicon | chromosome |
Accession | NZ_AP024333 | ||
Organism | Erwinia rhapontici strain MAFF 311155 |
Toxin (Protein)
Gene name | higB | Uniprot ID | - |
Locus tag | KI232_RS19835 | Protein ID | WP_133842340.1 |
Coordinates | 4294025..4294360 (+) | Length | 112 a.a. |
Antitoxin (Protein)
Gene name | higA | Uniprot ID | - |
Locus tag | KI232_RS19840 | Protein ID | WP_133842341.1 |
Coordinates | 4294365..4294682 (+) | Length | 106 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
KI232_RS19815 (ERHA55_43700) | 4289590..4290513 | - | 924 | WP_159336878.1 | sugar ABC transporter permease | - |
KI232_RS19820 (ERHA55_43710) | 4290579..4291865 | - | 1287 | WP_244874677.1 | sugar ABC transporter substrate-binding protein | - |
KI232_RS19825 (ERHA55_43720) | 4291888..4293045 | - | 1158 | WP_159336877.1 | PLP-dependent transferase | - |
KI232_RS19830 (ERHA55_43730) | 4293026..4293745 | - | 720 | WP_133842339.1 | FadR/GntR family transcriptional regulator | - |
KI232_RS19835 (ERHA55_43740) | 4294025..4294360 | + | 336 | WP_133842340.1 | toxin | Toxin |
KI232_RS19840 (ERHA55_43750) | 4294365..4294682 | + | 318 | WP_133842341.1 | type II toxin-antitoxin system MqsA family antitoxin | Antitoxin |
KI232_RS19845 (ERHA55_43760) | 4294757..4295500 | - | 744 | WP_212813282.1 | phosphatase PAP2 family protein | - |
KI232_RS19850 (ERHA55_43770) | 4295706..4298930 | - | 3225 | WP_167863355.1 | carbamoyl-phosphate synthase large subunit | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 112 a.a. Molecular weight: 12589.37 Da Isoelectric Point: 9.5577
>T38396 WP_133842340.1 NZ_AP024333:4294025-4294360 [Erwinia rhapontici]
VDAIFIELPPFARHRVDYFSDDAFRSLQNLLMLCPTCGDVIQHTGGLRKLRVGDAHRHKGKRGGSRVIYYWWQEQAHFLL
FTVYSKGEASDLSPAQRDSLRSLLANLTKGG
VDAIFIELPPFARHRVDYFSDDAFRSLQNLLMLCPTCGDVIQHTGGLRKLRVGDAHRHKGKRGGSRVIYYWWQEQAHFLL
FTVYSKGEASDLSPAQRDSLRSLLANLTKGG
Download Length: 336 bp
>T38396 NZ_AP024333:4294025-4294360 [Erwinia rhapontici]
GTGGATGCTATCTTTATTGAACTTCCGCCTTTCGCACGTCACCGTGTCGATTATTTTTCTGACGATGCATTTCGCAGTTT
GCAGAATCTGTTAATGCTCTGTCCCACCTGCGGTGATGTTATCCAGCACACCGGAGGGCTGCGTAAACTCAGAGTAGGCG
ATGCCCATCGCCATAAGGGAAAACGCGGAGGTTCACGGGTGATTTATTACTGGTGGCAGGAACAGGCACACTTTCTGCTG
TTCACTGTTTACAGCAAAGGAGAGGCAAGCGATCTCTCCCCGGCACAGCGCGACAGCTTACGTTCGCTGCTGGCAAACCT
GACTAAAGGAGGGTGA
GTGGATGCTATCTTTATTGAACTTCCGCCTTTCGCACGTCACCGTGTCGATTATTTTTCTGACGATGCATTTCGCAGTTT
GCAGAATCTGTTAATGCTCTGTCCCACCTGCGGTGATGTTATCCAGCACACCGGAGGGCTGCGTAAACTCAGAGTAGGCG
ATGCCCATCGCCATAAGGGAAAACGCGGAGGTTCACGGGTGATTTATTACTGGTGGCAGGAACAGGCACACTTTCTGCTG
TTCACTGTTTACAGCAAAGGAGAGGCAAGCGATCTCTCCCCGGCACAGCGCGACAGCTTACGTTCGCTGCTGGCAAACCT
GACTAAAGGAGGGTGA
Antitoxin
Download Length: 106 a.a. Molecular weight: 12022.83 Da Isoelectric Point: 7.4015
>AT38396 WP_133842341.1 NZ_AP024333:4294365-4294682 [Erwinia rhapontici]
MEKRDLYHELVEGFTALAEHHEGKKTLKTHRLAAKAEVVLAPEELRTIRENLQLSQAVFAQYLQTGLTTYQNWEQGRAKP
NKQAILLIRLIENESTTLEILAKLA
MEKRDLYHELVEGFTALAEHHEGKKTLKTHRLAAKAEVVLAPEELRTIRENLQLSQAVFAQYLQTGLTTYQNWEQGRAKP
NKQAILLIRLIENESTTLEILAKLA
Download Length: 318 bp
>AT38396 NZ_AP024333:4294365-4294682 [Erwinia rhapontici]
ATGGAAAAACGCGATCTTTACCATGAACTGGTCGAGGGGTTTACCGCGCTGGCTGAACATCACGAGGGCAAGAAAACGCT
GAAGACGCATCGCCTGGCGGCAAAAGCTGAGGTGGTACTTGCCCCGGAGGAATTGCGCACTATCCGTGAAAACTTACAGC
TTTCTCAGGCGGTCTTCGCACAGTACTTACAGACCGGATTAACCACCTATCAGAACTGGGAGCAGGGGCGGGCAAAGCCG
AATAAACAGGCCATTTTGCTGATCCGCTTAATTGAAAATGAGTCTACTACGCTGGAAATACTGGCAAAACTGGCTTAA
ATGGAAAAACGCGATCTTTACCATGAACTGGTCGAGGGGTTTACCGCGCTGGCTGAACATCACGAGGGCAAGAAAACGCT
GAAGACGCATCGCCTGGCGGCAAAAGCTGAGGTGGTACTTGCCCCGGAGGAATTGCGCACTATCCGTGAAAACTTACAGC
TTTCTCAGGCGGTCTTCGCACAGTACTTACAGACCGGATTAACCACCTATCAGAACTGGGAGCAGGGGCGGGCAAAGCCG
AATAAACAGGCCATTTTGCTGATCCGCTTAATTGAAAATGAGTCTACTACGCTGGAAATACTGGCAAAACTGGCTTAA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
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Antitoxin
Source | ID | Structure |
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