Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) higBA (relBE)/MqsA(antitoxin)
Location 4294025..4294682 Replicon chromosome
Accession NZ_AP024333
Organism Erwinia rhapontici strain MAFF 311155

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag KI232_RS19835 Protein ID WP_133842340.1
Coordinates 4294025..4294360 (+) Length 112 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag KI232_RS19840 Protein ID WP_133842341.1
Coordinates 4294365..4294682 (+) Length 106 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KI232_RS19815 (ERHA55_43700) 4289590..4290513 - 924 WP_159336878.1 sugar ABC transporter permease -
KI232_RS19820 (ERHA55_43710) 4290579..4291865 - 1287 WP_244874677.1 sugar ABC transporter substrate-binding protein -
KI232_RS19825 (ERHA55_43720) 4291888..4293045 - 1158 WP_159336877.1 PLP-dependent transferase -
KI232_RS19830 (ERHA55_43730) 4293026..4293745 - 720 WP_133842339.1 FadR/GntR family transcriptional regulator -
KI232_RS19835 (ERHA55_43740) 4294025..4294360 + 336 WP_133842340.1 toxin Toxin
KI232_RS19840 (ERHA55_43750) 4294365..4294682 + 318 WP_133842341.1 type II toxin-antitoxin system MqsA family antitoxin Antitoxin
KI232_RS19845 (ERHA55_43760) 4294757..4295500 - 744 WP_212813282.1 phosphatase PAP2 family protein -
KI232_RS19850 (ERHA55_43770) 4295706..4298930 - 3225 WP_167863355.1 carbamoyl-phosphate synthase large subunit -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

(23-98)


Sequences


Toxin        


Download         Length: 112 a.a.        Molecular weight: 12589.37 Da        Isoelectric Point: 9.5577

>T38396 WP_133842340.1 NZ_AP024333:4294025-4294360 [Erwinia rhapontici]
VDAIFIELPPFARHRVDYFSDDAFRSLQNLLMLCPTCGDVIQHTGGLRKLRVGDAHRHKGKRGGSRVIYYWWQEQAHFLL
FTVYSKGEASDLSPAQRDSLRSLLANLTKGG

Download         Length: 336 bp

>T38396 NZ_AP024333:4294025-4294360 [Erwinia rhapontici]
GTGGATGCTATCTTTATTGAACTTCCGCCTTTCGCACGTCACCGTGTCGATTATTTTTCTGACGATGCATTTCGCAGTTT
GCAGAATCTGTTAATGCTCTGTCCCACCTGCGGTGATGTTATCCAGCACACCGGAGGGCTGCGTAAACTCAGAGTAGGCG
ATGCCCATCGCCATAAGGGAAAACGCGGAGGTTCACGGGTGATTTATTACTGGTGGCAGGAACAGGCACACTTTCTGCTG
TTCACTGTTTACAGCAAAGGAGAGGCAAGCGATCTCTCCCCGGCACAGCGCGACAGCTTACGTTCGCTGCTGGCAAACCT
GACTAAAGGAGGGTGA

Antitoxin


Download         Length: 106 a.a.        Molecular weight: 12022.83 Da        Isoelectric Point: 7.4015

>AT38396 WP_133842341.1 NZ_AP024333:4294365-4294682 [Erwinia rhapontici]
MEKRDLYHELVEGFTALAEHHEGKKTLKTHRLAAKAEVVLAPEELRTIRENLQLSQAVFAQYLQTGLTTYQNWEQGRAKP
NKQAILLIRLIENESTTLEILAKLA

Download         Length: 318 bp

>AT38396 NZ_AP024333:4294365-4294682 [Erwinia rhapontici]
ATGGAAAAACGCGATCTTTACCATGAACTGGTCGAGGGGTTTACCGCGCTGGCTGAACATCACGAGGGCAAGAAAACGCT
GAAGACGCATCGCCTGGCGGCAAAAGCTGAGGTGGTACTTGCCCCGGAGGAATTGCGCACTATCCGTGAAAACTTACAGC
TTTCTCAGGCGGTCTTCGCACAGTACTTACAGACCGGATTAACCACCTATCAGAACTGGGAGCAGGGGCGGGCAAAGCCG
AATAAACAGGCCATTTTGCTGATCCGCTTAATTGAAAATGAGTCTACTACGCTGGAAATACTGGCAAAACTGGCTTAA

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure

References