Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/MqsA(antitoxin)
Location 4356815..4357472 Replicon chromosome
Accession NZ_AP024331
Organism Erwinia rhapontici strain MAFF 311154

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag KI233_RS20060 Protein ID WP_133842340.1
Coordinates 4356815..4357150 (+) Length 112 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag KI233_RS20065 Protein ID WP_133842341.1
Coordinates 4357155..4357472 (+) Length 106 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KI233_RS20040 (ERHA54_41470) 4352379..4353302 - 924 WP_159336878.1 sugar ABC transporter permease -
KI233_RS20045 (ERHA54_41480) 4353368..4354654 - 1287 WP_244874677.1 sugar ABC transporter substrate-binding protein -
KI233_RS20050 (ERHA54_41490) 4354677..4355834 - 1158 WP_159336877.1 PLP-dependent transferase -
KI233_RS20055 (ERHA54_41500) 4355815..4356534 - 720 WP_133842339.1 FadR/GntR family transcriptional regulator -
KI233_RS20060 (ERHA54_41510) 4356815..4357150 + 336 WP_133842340.1 toxin Toxin
KI233_RS20065 (ERHA54_41520) 4357155..4357472 + 318 WP_133842341.1 type II toxin-antitoxin system MqsA family antitoxin Antitoxin
KI233_RS20070 (ERHA54_41530) 4357547..4358290 - 744 WP_212813282.1 phosphatase PAP2 family protein -
KI233_RS20075 (ERHA54_41540) 4358496..4361720 - 3225 WP_167863355.1 carbamoyl-phosphate synthase large subunit -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Antitoxin MqsA/HigA-2

(23-98)


Sequences

Toxin        


Download         Length: 112 a.a.        Molecular weight: 12589.37 Da        Isoelectric Point: 9.5577

>T38385 WP_133842340.1 NZ_AP024331:4356815-4357150 [Erwinia rhapontici]
VDAIFIELPPFARHRVDYFSDDAFRSLQNLLMLCPTCGDVIQHTGGLRKLRVGDAHRHKGKRGGSRVIYYWWQEQAHFLL
FTVYSKGEASDLSPAQRDSLRSLLANLTKGG

Download         Length: 336 bp

>T38385 NZ_AP024331:4356815-4357150 [Erwinia rhapontici]
GTGGATGCTATCTTTATTGAACTTCCGCCTTTCGCACGTCACCGTGTCGATTATTTTTCTGACGATGCATTTCGCAGTTT
GCAGAATCTGTTAATGCTCTGTCCCACCTGCGGTGATGTTATCCAGCACACCGGAGGGCTGCGTAAACTCAGAGTAGGCG
ATGCCCATCGCCATAAGGGAAAACGCGGAGGTTCACGGGTGATTTATTACTGGTGGCAGGAACAGGCACACTTTCTGCTG
TTCACTGTTTACAGCAAAGGAGAGGCAAGCGATCTCTCCCCGGCACAGCGCGACAGCTTACGTTCGCTGCTGGCAAACCT
GACTAAAGGAGGGTGA

Antitoxin


Download         Length: 106 a.a.        Molecular weight: 12022.83 Da        Isoelectric Point: 7.4015

>AT38385 WP_133842341.1 NZ_AP024331:4357155-4357472 [Erwinia rhapontici]
MEKRDLYHELVEGFTALAEHHEGKKTLKTHRLAAKAEVVLAPEELRTIRENLQLSQAVFAQYLQTGLTTYQNWEQGRAKP
NKQAILLIRLIENESTTLEILAKLA

Download         Length: 318 bp

>AT38385 NZ_AP024331:4357155-4357472 [Erwinia rhapontici]
ATGGAAAAACGCGATCTTTACCATGAACTGGTCGAGGGGTTTACCGCGCTGGCTGAACATCACGAGGGCAAGAAAACGCT
GAAGACGCATCGCCTGGCGGCAAAAGCTGAGGTGGTACTTGCCCCGGAGGAATTGCGCACTATCCGTGAAAACTTACAGC
TTTCTCAGGCGGTCTTCGCACAGTACTTACAGACCGGATTAACCACCTATCAGAACTGGGAGCAGGGGCGGGCAAAGCCG
AATAAACAGGCCATTTTGCTGATCCGCTTAATTGAAAATGAGTCTACTACGCTGGAAATACTGGCAAAACTGGCTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References