Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 2447004..2447188 Replicon chromosome
Accession NZ_AP024318
Organism Staphylococcus aureus strain S36

Toxin (Protein)


Gene name SprA2 Uniprot ID A0A2P7CQJ7
Locus tag K5606_RS12115 Protein ID WP_000482647.1
Coordinates 2447081..2447188 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 2447004..2447064 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
K5606_RS12100 2442458..2442625 - 168 WP_001798790.1 hypothetical protein -
K5606_RS12105 2442856..2444589 - 1734 WP_000486511.1 ABC transporter ATP-binding protein -
K5606_RS12110 2444614..2446377 - 1764 WP_001064818.1 ABC transporter ATP-binding protein -
- 2447004..2447064 + 61 - - Antitoxin
K5606_RS12115 2447081..2447188 - 108 WP_000482647.1 type I toxin-antitoxin system Fst family toxin Toxin
K5606_RS12120 2447322..2447708 - 387 WP_000779355.1 flippase GtxA -
K5606_RS12125 2447975..2449117 + 1143 WP_001176859.1 glycerate kinase -
K5606_RS12130 2449177..2449836 + 660 WP_000831300.1 hypothetical protein -
K5606_RS12135 2450024..2451235 + 1212 WP_001191974.1 multidrug effflux MFS transporter -
K5606_RS12140 2451358..2451831 - 474 WP_000456489.1 GyrI-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4012.76 Da        Isoelectric Point: 10.4935

>T38366 WP_000482647.1 NZ_AP024318:c2447188-2447081 [Staphylococcus aureus]
MFNLLIDIMTSALSGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

>T38366 NZ_AP024318:c2447188-2447081 [Staphylococcus aureus]
ATGTTCAATTTATTAATTGACATCATGACTTCAGCTTTAAGCGGCTGTCTTGTTGCGTTTTTTGCACATTGGTTACGAAC
GCGCAACAATAAAAAAGGTGACAAATAA

Antitoxin


Download         Length: 61 bp

>AT38366 NZ_AP024318:2447004-2447064 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2P7CQJ7

Antitoxin

Download structure file

References