Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2182501..2182718 Replicon chromosome
Accession NZ_AP024315
Organism Staphylococcus aureus strain BDH17

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag K5602_RS10710 Protein ID WP_001802298.1
Coordinates 2182614..2182718 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF1
Locus tag -
Coordinates 2182501..2182556 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
K5602_RS10690 2178640..2179305 - 666 WP_001024099.1 SDR family oxidoreductase -
K5602_RS10695 2179457..2179777 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
K5602_RS10700 2179779..2180759 + 981 WP_000019735.1 CDF family zinc efflux transporter CzrB -
K5602_RS10705 2181025..2182116 + 1092 WP_000495673.1 hypothetical protein -
- 2182501..2182556 + 56 - - Antitoxin
K5602_RS10710 2182614..2182718 - 105 WP_001802298.1 hypothetical protein Toxin
K5602_RS10715 2183398..2183556 + 159 WP_001792784.1 hypothetical protein -
K5602_RS10720 2183992..2184084 + 93 WP_000220902.1 hypothetical protein -
K5602_RS10725 2184214..2185071 - 858 WP_000370942.1 HAD family hydrolase -
K5602_RS10730 2185139..2185921 - 783 WP_000908191.1 ABC transporter ATP-binding protein -
K5602_RS10735 2186211..2186819 - 609 WP_000101714.1 TIR domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T38352 WP_001802298.1 NZ_AP024315:c2182718-2182614 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T38352 NZ_AP024315:c2182718-2182614 [Staphylococcus aureus]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTGATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin


Download         Length: 56 bp

>AT38352 NZ_AP024315:2182501-2182556 [Staphylococcus aureus]
AAAAAGGGCAACACTCGGAAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References