Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2243337..2243554 Replicon chromosome
Accession NZ_AP024313
Organism Staphylococcus aureus strain N1195

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag K5605_RS11130 Protein ID WP_001802298.1
Coordinates 2243450..2243554 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF1
Locus tag -
Coordinates 2243337..2243392 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
K5605_RS11110 2239476..2240141 - 666 WP_001024099.1 SDR family oxidoreductase -
K5605_RS11115 2240293..2240613 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
K5605_RS11120 2240615..2241595 + 981 WP_000019735.1 CDF family zinc efflux transporter CzrB -
K5605_RS11125 2241861..2242952 + 1092 WP_000495673.1 hypothetical protein -
- 2243337..2243392 + 56 - - Antitoxin
K5605_RS11130 2243450..2243554 - 105 WP_001802298.1 hypothetical protein Toxin
K5605_RS11135 2244234..2244392 + 159 WP_001792784.1 hypothetical protein -
K5605_RS11140 2244828..2244920 + 93 WP_000220902.1 hypothetical protein -
K5605_RS11145 2245050..2245907 - 858 WP_000370942.1 HAD family hydrolase -
K5605_RS11150 2245975..2246757 - 783 WP_000908191.1 ABC transporter ATP-binding protein -
K5605_RS11155 2247047..2247655 - 609 WP_000101714.1 TIR domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T38340 WP_001802298.1 NZ_AP024313:c2243554-2243450 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T38340 NZ_AP024313:c2243554-2243450 [Staphylococcus aureus]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTGATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin


Download         Length: 56 bp

>AT38340 NZ_AP024313:2243337-2243392 [Staphylococcus aureus]
AAAAAGGGCAACACTCGGAAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References