Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2247315..2247532 Replicon chromosome
Accession NZ_AP024311
Organism Staphylococcus aureus strain THI2018-120

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag ST1232TP_RS11155 Protein ID WP_001802298.1
Coordinates 2247428..2247532 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF1
Locus tag -
Coordinates 2247315..2247370 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ST1232TP_RS11135 2243454..2244119 - 666 WP_001024099.1 SDR family oxidoreductase -
ST1232TP_RS11140 2244271..2244591 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
ST1232TP_RS11145 2244593..2245573 + 981 WP_000019735.1 CDF family zinc efflux transporter CzrB -
ST1232TP_RS11150 2245839..2246930 + 1092 WP_000495673.1 hypothetical protein -
- 2247315..2247370 + 56 - - Antitoxin
ST1232TP_RS11155 2247428..2247532 - 105 WP_001802298.1 hypothetical protein Toxin
ST1232TP_RS11160 2248212..2248370 + 159 WP_001792784.1 hypothetical protein -
ST1232TP_RS11165 2248806..2248898 + 93 WP_000220902.1 hypothetical protein -
ST1232TP_RS11170 2249028..2249885 - 858 WP_000370942.1 HAD family hydrolase -
ST1232TP_RS11175 2249953..2250735 - 783 WP_000908191.1 ABC transporter ATP-binding protein -
ST1232TP_RS11180 2251025..2251633 - 609 WP_000101714.1 TIR domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T38328 WP_001802298.1 NZ_AP024311:c2247532-2247428 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T38328 NZ_AP024311:c2247532-2247428 [Staphylococcus aureus]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTGATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin


Download         Length: 56 bp

>AT38328 NZ_AP024311:2247315-2247370 [Staphylococcus aureus]
AAAAAGGGCAACACTCGGAAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References