Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-RelB
Location 185954..186473 Replicon chromosome
Accession NZ_AP024276
Organism Streptococcus parasuis strain SUT-286

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag L6410_RS00960 Protein ID WP_237395623.1
Coordinates 186216..186473 (+) Length 86 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag L6410_RS00955 Protein ID WP_172028539.1
Coordinates 185954..186214 (+) Length 87 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
L6410_RS00940 (SUT286_01700) 181743..182525 + 783 WP_237395618.1 TatD family hydrolase -
L6410_RS00945 (SUT286_01710) 182509..183075 + 567 WP_237395620.1 ribonuclease M5 -
L6410_RS00950 (SUT286_01720) 183463..185430 + 1968 WP_237395621.1 retron Ec67 family RNA-directed DNA polymerase/endonuclease -
L6410_RS00955 (SUT286_01730) 185954..186214 + 261 WP_172028539.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
L6410_RS00960 (SUT286_01740) 186216..186473 + 258 WP_237395623.1 Txe/YoeB family addiction module toxin Toxin
L6410_RS00965 (SUT286_01750) 186588..187463 + 876 WP_172055060.1 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))- dimethyltransferase RsmA -
L6410_RS00970 (SUT286_01760) 187529..187696 + 168 WP_237395624.1 hypothetical protein -
L6410_RS00975 (SUT286_01770) 187817..188362 - 546 WP_172055062.1 cysteine hydrolase family protein -
L6410_RS00980 (SUT286_01780) 188955..190718 + 1764 WP_237395626.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-75)


Sequences

Toxin        


Download         Length: 86 a.a.        Molecular weight: 10265.71 Da        Isoelectric Point: 6.7246

>T38281 WP_237395623.1 NZ_AP024276:186216-186473 [Streptococcus parasuis]
MGIHFTEDAWEDYLYWQGQDKKTLKRINKIIKDMQRHPFEGIAKPEPLKYDYQGAWSRKIDAENRLIYMVEADQLYILSL
KDHYG

Download         Length: 258 bp

>T38281 NZ_AP024276:186216-186473 [Streptococcus parasuis]
ATGGGAATCCATTTTACAGAGGATGCTTGGGAAGACTATCTCTACTGGCAGGGTCAGGATAAGAAAACACTGAAGAGAAT
CAATAAGATTATCAAGGATATGCAGCGACATCCTTTTGAAGGCATTGCCAAACCAGAACCTTTGAAGTATGACTATCAAG
GTGCCTGGTCAAGAAAGATTGATGCGGAAAATCGGTTGATTTATATGGTGGAGGCCGACCAGTTGTATATCTTGTCGCTA
AAGGACCATTATGGGTGA

Antitoxin


Download         Length: 87 a.a.        Molecular weight: 9973.33 Da        Isoelectric Point: 5.6227

>AT38281 WP_172028539.1 NZ_AP024276:185954-186214 [Streptococcus parasuis]
MEAIVYSHFRNHLKDYMKKVNDEFEPLVVVNKNPEEDIVVLSKSEWDSLQETLAVARNTYLSQKVLRGMAQVKAGQTQER
HLIEAD

Download         Length: 261 bp

>AT38281 NZ_AP024276:185954-186214 [Streptococcus parasuis]
ATGGAAGCTATTGTATATTCCCATTTTCGAAATCACTTAAAGGACTATATGAAAAAGGTAAATGACGAGTTTGAGCCTTT
GGTCGTGGTTAATAAAAATCCAGAAGAAGATATTGTTGTACTCTCAAAGAGCGAGTGGGATAGTTTACAAGAAACCCTCG
CTGTTGCTCGGAACACTTATCTGTCTCAAAAAGTTTTGCGTGGTATGGCTCAAGTCAAAGCAGGGCAAACCCAAGAACGC
CATCTGATAGAGGCAGACTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References