Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | I | Classification (family/domain) | TMCS/- |
Location | 2339366..2339945 | Replicon | chromosome |
Accession | NZ_AP024203 | ||
Organism | Staphylococcus aureus strain SA23-1 |
Toxin (Protein)
Gene name | MW1434 | Uniprot ID | A0A4P7P609 |
Locus tag | SA231_RS11535 | Protein ID | WP_001025401.1 |
Coordinates | 2339700..2339945 (-) | Length | 82 a.a. |
Antitoxin (RNA)
Gene name | MW1433 | ||
Locus tag | - | ||
Coordinates | 2339366..2339731 (+) |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
SA231_RS11495 (2336085) | 2336085..2336666 | - | 582 | WP_176426981.1 | DUF2815 family protein | - |
SA231_RS11500 (2336692) | 2336692..2337858 | - | 1167 | WP_000762547.1 | DUF2800 domain-containing protein | - |
SA231_RS11505 (2337855) | 2337855..2338217 | - | 363 | WP_229344986.1 | hypothetical protein | - |
SA231_RS11510 (2338232) | 2338232..2338555 | - | 324 | WP_000175001.1 | hypothetical protein | - |
SA231_RS11515 (2338634) | 2338634..2338795 | - | 162 | WP_001285954.1 | DUF1270 domain-containing protein | - |
SA231_RS11520 (2338808) | 2338808..2339071 | - | 264 | WP_001124160.1 | helix-turn-helix domain-containing protein | - |
SA231_RS11525 (2339096) | 2339096..2339311 | - | 216 | WP_001097552.1 | hypothetical protein | - |
SA231_RS11530 (2339366) | 2339366..2339731 | + | 366 | WP_001128433.1 | hypothetical protein | Antitoxin |
SA231_RS11535 (2339700) | 2339700..2339945 | - | 246 | WP_001025401.1 | DUF2829 domain-containing protein | Toxin |
SA231_RS11540 (2340001) | 2340001..2340210 | + | 210 | WP_000642492.1 | hypothetical protein | - |
SA231_RS11545 (2340200) | 2340200..2340343 | - | 144 | WP_000939498.1 | hypothetical protein | - |
SA231_RS11550 (2340372) | 2340372..2341148 | - | 777 | WP_001148544.1 | Rha family transcriptional regulator | - |
SA231_RS11555 (2341162) | 2341162..2341398 | - | 237 | WP_001121027.1 | helix-turn-helix transcriptional regulator | - |
SA231_RS11560 (2341550) | 2341550..2341864 | + | 315 | WP_000333630.1 | helix-turn-helix transcriptional regulator | - |
SA231_RS11565 (2341877) | 2341877..2342338 | + | 462 | WP_000525004.1 | hypothetical protein | - |
SA231_RS11570 (2342356) | 2342356..2342940 | + | 585 | WP_000825948.1 | hypothetical protein | - |
SA231_RS11575 (2343170) | 2343170..2343316 | + | 147 | WP_001013104.1 | hypothetical protein | - |
SA231_RS11580 (2343313) | 2343313..2343927 | - | 615 | WP_000191459.1 | hypothetical protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
- | inside | Prophage | - | gnd | 2298645..2367853 | 69208 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 82 a.a. Molecular weight: 9468.72 Da Isoelectric Point: 5.7783
>T38141 WP_001025401.1 NZ_AP024203:c2339945-2339700 [Staphylococcus aureus]
MNIQEATKIATKNLVSMTRKDWKESHRTKILPTNDSFLQCIISNSDGTNLIRYWQPSADDLMANDWEVINPTRDQELLKQ
F
MNIQEATKIATKNLVSMTRKDWKESHRTKILPTNDSFLQCIISNSDGTNLIRYWQPSADDLMANDWEVINPTRDQELLKQ
F
Download Length: 246 bp
>T38141 NZ_AP024203:c2339945-2339700 [Staphylococcus aureus]
ATGAACATTCAAGAAGCAACTAAGATAGCTACAAAAAATCTTGTCTCTATGACACGGAAAGATTGGAAAGAAAGTCATCG
AACTAAGATATTACCAACAAATGATAGTTTTTTACAATGCATCATTTCAAATAGCGATGGGACAAACCTTATCAGATATT
GGCAACCTTCAGCCGATGACCTCATGGCAAATGATTGGGAAGTTATAAACCCAACTAGAGACCAGGAATTATTGAAGCAA
TTTTAG
ATGAACATTCAAGAAGCAACTAAGATAGCTACAAAAAATCTTGTCTCTATGACACGGAAAGATTGGAAAGAAAGTCATCG
AACTAAGATATTACCAACAAATGATAGTTTTTTACAATGCATCATTTCAAATAGCGATGGGACAAACCTTATCAGATATT
GGCAACCTTCAGCCGATGACCTCATGGCAAATGATTGGGAAGTTATAAACCCAACTAGAGACCAGGAATTATTGAAGCAA
TTTTAG
Antitoxin
Download Length: 366 bp
>AT38141 NZ_AP024203:2339366-2339731 [Staphylococcus aureus]
ATGCCCTTGATATCTGATGAATTTGATACACTTACTAAAGACCAACAATATATCTTGTCCGTACTCTACAAAGATTATTT
AGAATGTGTAAAGTTAGGTTCGGTTAAATTAACCTGCAATAATTTTGGAAGTGCTAAAGATATACATACAAAGTATTTTC
AAAAACTACATTTCGAAGATGTAAAATACGATTTAAATAAACTTAAAAACTCTGGGTTCCTAAACGGCGTGTATGCTAGT
AACACTATTTATCATGTAACAATTTCAGACAAGACTGTTGTTTACTTTGAAAATGAGTTTAAAAACAATTTAAAAAGTAT
CATTGATAGCATTTCTAAAATTGCTTCAATAATTCCTGGTCTCTAG
ATGCCCTTGATATCTGATGAATTTGATACACTTACTAAAGACCAACAATATATCTTGTCCGTACTCTACAAAGATTATTT
AGAATGTGTAAAGTTAGGTTCGGTTAAATTAACCTGCAATAATTTTGGAAGTGCTAAAGATATACATACAAAGTATTTTC
AAAAACTACATTTCGAAGATGTAAAATACGATTTAAATAAACTTAAAAACTCTGGGTTCCTAAACGGCGTGTATGCTAGT
AACACTATTTATCATGTAACAATTTCAGACAAGACTGTTGTTTACTTTGAAAATGAGTTTAAAAACAATTTAAAAAGTAT
CATTGATAGCATTTCTAAAATTGCTTCAATAATTCCTGGTCTCTAG
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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