Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/Txe-RelB
Location 2469751..2470274 Replicon chromosome
Accession NZ_AP024201
Organism Staphylococcus argenteus strain Tokyo13069

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag JN167_RS11895 Protein ID WP_047527363.1
Coordinates 2469751..2470017 (-) Length 89 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag JN167_RS11900 Protein ID WP_047431397.1
Coordinates 2470017..2470274 (-) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JN167_RS11875 2465113..2466300 - 1188 WP_047527354.1 MFS transporter -
JN167_RS11880 2466644..2467417 - 774 WP_000072156.1 iron export ABC transporter permease subunit FetB -
JN167_RS11885 2467410..2468072 - 663 WP_047527359.1 ATP-binding cassette domain-containing protein -
JN167_RS11890 2468320..2469396 - 1077 WP_047527361.1 M42 family metallopeptidase -
JN167_RS11895 2469751..2470017 - 267 WP_047527363.1 Txe/YoeB family addiction module toxin Toxin
JN167_RS11900 2470017..2470274 - 258 WP_047431397.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
JN167_RS11905 2470630..2471094 + 465 WP_047431401.1 DUF1307 domain-containing protein -
JN167_RS11910 2471262..2472839 - 1578 WP_047527367.1 FMN-binding glutamate synthase family protein -
JN167_RS11915 2473033..2473782 + 750 WP_047527368.1 hypothetical protein -
JN167_RS11920 2474009..2475202 - 1194 WP_000675397.1 MFS transporter -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(9-87)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-68)


Sequences

Toxin        


Download         Length: 89 a.a.        Molecular weight: 10592.38 Da        Isoelectric Point: 10.4663

>T38134 WP_047527363.1 NZ_AP024201:c2470017-2469751 [Staphylococcus argenteus]
MSNYTVKIKNSAKSDLKKIKNSYLKKSFLKIVETLKNDPYKITQSFEKLEPKYLVRYLRKINHKHRVVYTVDDRNKEVLI
LSAWSHYD

Download         Length: 267 bp

>T38134 NZ_AP024201:c2470017-2469751 [Staphylococcus argenteus]
ATGAGCAATTACACGGTTAAGATTAAAAATTCGGCGAAATCAGATTTAAAGAAAATAAAAAATTCTTATTTAAAGAAGTC
GTTTTTAAAAATTGTTGAAACTTTAAAAAATGATCCGTATAAAATAACACAATCCTTTGAAAAATTAGAACCTAAATATT
TAGTGAGATATTTAAGAAAAATTAACCATAAGCACAGGGTAGTCTATACCGTAGATGATCGAAATAAAGAGGTATTAATA
CTATCGGCGTGGTCACATTATGATTAA

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9760.71 Da        Isoelectric Point: 4.1232

>AT38134 WP_047431397.1 NZ_AP024201:c2470274-2470017 [Staphylococcus argenteus]
MIITSPTEARKDFYQLLKNVNNNHEPIYISGNNAENNAVIIGLDDWKSIQETIYLESTGTMDKVREREKDNSGTTNIDDI
DWDNL

Download         Length: 258 bp

>AT38134 NZ_AP024201:c2470274-2470017 [Staphylococcus argenteus]
ATGATTATCACTAGCCCTACAGAAGCGAGAAAAGATTTTTATCAATTACTAAAAAATGTTAATAATAATCACGAGCCAAT
TTATATTAGTGGCAATAATGCCGAAAATAATGCTGTGATTATAGGTTTAGATGATTGGAAAAGTATACAAGAAACAATAT
ATCTGGAATCTACTGGTACAATGGACAAAGTAAGAGAAAGAGAAAAAGATAATAGTGGTACAACAAATATAGATGATATT
GATTGGGATAATCTTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References