Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type I Classification (family/domain) sprA1-sprA1AS/-
Location 1828863..1829043 Replicon chromosome
Accession NZ_AP024201
Organism Staphylococcus argenteus strain Tokyo13069

Toxin (Protein)


Gene name sprA1 Uniprot ID -
Locus tag JN167_RS08480 Protein ID WP_001801861.1
Coordinates 1828863..1828958 (+) Length 32 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 1828986..1829043 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JN167_RS08450 1824892..1825518 + 627 WP_047526911.1 hypothetical protein -
JN167_RS08455 1825559..1825900 + 342 WP_047526913.1 DUF3969 family protein -
JN167_RS08460 1826001..1826573 + 573 WP_047526915.1 hypothetical protein -
JN167_RS08465 1826771..1827328 - 558 WP_047526917.1 ImmA/IrrE family metallo-endopeptidase -
JN167_RS08470 1827513..1827959 - 447 WP_031787841.1 DUF1433 domain-containing protein -
JN167_RS08475 1828081..1828338 - 258 WP_047526919.1 IS3 family transposase -
JN167_RS08480 1828863..1828958 + 96 WP_001801861.1 type I toxin-antitoxin system Fst family toxin PepA1 Toxin
- 1828986..1829043 - 58 - - Antitoxin
JN167_RS08485 1829081..1829182 + 102 WP_047526922.1 hypothetical protein -
JN167_RS08490 1829317..1829763 - 447 WP_047526923.1 DUF1433 domain-containing protein -
JN167_RS08495 1829763..1830206 - 444 WP_047526925.1 DUF1433 domain-containing protein -
JN167_RS08500 1830206..1830649 - 444 WP_047526927.1 DUF1433 domain-containing protein -
JN167_RS08505 1831276..1832496 - 1221 WP_047526928.1 restriction endonuclease subunit S -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin


No domain identified.



Sequences


Toxin        


Download         Length: 32 a.a.        Molecular weight: 3554.32 Da        Isoelectric Point: 10.4449

>T38124 WP_001801861.1 NZ_AP024201:1828863-1828958 [Staphylococcus argenteus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Download         Length: 96 bp

>T38124 NZ_AP024201:1828863-1828958 [Staphylococcus argenteus]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin


Download         Length: 58 bp

>AT38124 NZ_AP024201:c1829043-1828986 [Staphylococcus argenteus]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Download structure file

References