Detailed information of TA system TA038123

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprG-sprF/-
• Location: 984067..984316
• Replicon: chromosome
• Accession: NZ_AP024201
• Organism: Staphylococcus argenteus strain Tokyo13069

Toxin (Protein)

• Gene name: SprG2
• Uniprot ID: -
• Locus tag: JN167_RS04645
• Protein ID: WP_014373809.1
• Coordinates: 984067..984174 (+)
• Length: 36 a.a.

Antitoxin (RNA)

Gene name	SprF2
Locus tag	-
Coordinates	984169..984316 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
JN167_RS04620	980746..981315	-	570	WP_000287261.1	competence protein ComK	-
JN167_RS04625	981525..981743	+	219	WP_000876831.1	IDEAL domain-containing protein	-
JN167_RS04630	981824..982810	-	987	WP_047526294.1	lipoate--protein ligase	-
JN167_RS04635	983005..983181	+	177	WP_000214898.1	YkvS family protein	-
JN167_RS04640	983196..983798	+	603	WP_031787353.1	CPBP family intramembrane metalloprotease	-
JN167_RS04645	984067..984174	+	108	WP_014373809.1	putative holin-like toxin	Toxin
-	984169..984316	-	148	-	-	Antitoxin
JN167_RS04650	984810..985094	+	285	WP_000790905.1	lactococcin 972 family bacteriocin	-
JN167_RS04655	985138..987102	+	1965	WP_047526299.1	bacteriocin-associated integral membrane family protein	-
JN167_RS04660	987105..987425	+	321	WP_047526301.1	YxeA family protein	-
JN167_RS04665	987422..988063	+	642	WP_047526302.1	ABC transporter ATP-binding protein	-
JN167_RS04670	988151..988411	-	261	WP_169929182.1	hypothetical protein	-
JN167_RS04675	988726..989013	+	288	WP_000410715.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (3-35)

Sequences

Toxin

Protein

• Length: 36 a.a.
• Molecular weight: 3815.72 Da
• Isoelectric Point: 10.8004

>T38123 WP_014373809.1 NZ_AP024201:984067-984174 [Staphylococcus argenteus]
VISIANALHLMLSFGMFIVTFIGIVVAIINLNNKK

Nucleotide

• Length: 108 bp

>T38123 NZ_AP024201:984067-984174 [Staphylococcus argenteus]
GTGATATCTATTGCAAACGCATTACATTTAATGTTAAGTTTCGGTATGTTTATCGTAACTTTCATTGGTATAGTAGTCGC
AATAATTAATTTAAACAATAAAAAATAA

Antitoxin

Nucleotide

• Length: 148 bp

>AT38123 NZ_AP024201:c984316-984169 [Staphylococcus argenteus]
CAATTTTAAAAAAGATATGTTACTATAAAAATGTAAAAAGACGACATGCAGGAACATGTCGCCTATTGAGCCCGTTAAAA
AGACGGTGACTAAATGAGATTTTCTTTAACCATCATTCTTTGTCAAAGTTATGAAATGATGGTTATTT

Structures

Antitoxin