Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprG2-SprA2AS/-
Location 984067..984284 Replicon chromosome
Accession NZ_AP024201
Organism Staphylococcus argenteus strain Tokyo13069

Toxin (Protein)


Gene name SprG2 Uniprot ID -
Locus tag JN167_RS04645 Protein ID WP_014373809.1
Coordinates 984067..984174 (+) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 984169..984284 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JN167_RS04620 980746..981315 - 570 WP_000287261.1 competence protein ComK -
JN167_RS04625 981525..981743 + 219 WP_000876831.1 IDEAL domain-containing protein -
JN167_RS04630 981824..982810 - 987 WP_047526294.1 lipoate--protein ligase -
JN167_RS04635 983005..983181 + 177 WP_000214898.1 YkvS family protein -
JN167_RS04640 983196..983798 + 603 WP_031787353.1 CPBP family intramembrane metalloprotease -
JN167_RS04645 984067..984174 + 108 WP_014373809.1 putative holin-like toxin Toxin
- 984169..984284 - 116 - - Antitoxin
JN167_RS04650 984810..985094 + 285 WP_000790905.1 lactococcin 972 family bacteriocin -
JN167_RS04655 985138..987102 + 1965 WP_047526299.1 bacteriocin-associated integral membrane family protein -
JN167_RS04660 987105..987425 + 321 WP_047526301.1 YxeA family protein -
JN167_RS04665 987422..988063 + 642 WP_047526302.1 ABC transporter ATP-binding protein -
JN167_RS04670 988151..988411 - 261 WP_169929182.1 hypothetical protein -
JN167_RS04675 988726..989013 + 288 WP_000410715.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Small toxic protein BsrE-like

(3-35)


Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 3815.72 Da        Isoelectric Point: 10.8004

>T38122 WP_014373809.1 NZ_AP024201:984067-984174 [Staphylococcus argenteus]
VISIANALHLMLSFGMFIVTFIGIVVAIINLNNKK

Download         Length: 108 bp

>T38122 NZ_AP024201:984067-984174 [Staphylococcus argenteus]
GTGATATCTATTGCAAACGCATTACATTTAATGTTAAGTTTCGGTATGTTTATCGTAACTTTCATTGGTATAGTAGTCGC
AATAATTAATTTAAACAATAAAAAATAA

Antitoxin


Download         Length: 116 bp

>AT38122 NZ_AP024201:c984284-984169 [Staphylococcus argenteus]
GTAAAAAGACGACATGCAGGAACATGTCGCCTATTGAGCCCGTTAAAAAGACGGTGACTAAATGAGATTTTCTTTAACCA
TCATTCTTTGTCAAAGTTATGAAATGATGGTTATTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References