Detailed information of TA system TA038110

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprA1-sprA1AS/-
• Location: 1828861..1829041
• Replicon: chromosome
• Accession: NZ_AP024200
• Organism: Staphylococcus argenteus strain Tokyo13064

Toxin (Protein)

• Gene name: sprA1
• Uniprot ID: -
• Locus tag: JN157_RS08485
• Protein ID: WP_001801861.1
• Coordinates: 1828861..1828956 (+)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	1828984..1829041 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
JN157_RS08455	1824890..1825516	+	627	WP_047526911.1	hypothetical protein	-
JN157_RS08460	1825557..1825898	+	342	WP_047526913.1	DUF3969 family protein	-
JN157_RS08465	1825999..1826571	+	573	WP_047526915.1	hypothetical protein	-
JN157_RS08470	1826769..1827326	-	558	WP_047526917.1	ImmA/IrrE family metallo-endopeptidase	-
JN157_RS08475	1827511..1827957	-	447	WP_031787841.1	DUF1433 domain-containing protein	-
JN157_RS08480	1828079..1828336	-	258	WP_047526919.1	IS3 family transposase	-
JN157_RS08485	1828861..1828956	+	96	WP_001801861.1	type I toxin-antitoxin system Fst family toxin PepA1	Toxin
-	1828984..1829041	-	58	-	-	Antitoxin
JN157_RS08490	1829079..1829180	+	102	WP_047526922.1	hypothetical protein	-
JN157_RS08495	1829315..1829761	-	447	WP_047526923.1	DUF1433 domain-containing protein	-
JN157_RS08500	1829761..1830204	-	444	WP_047526925.1	DUF1433 domain-containing protein	-
JN157_RS08505	1830204..1830647	-	444	WP_047526927.1	DUF1433 domain-containing protein	-
JN157_RS08510	1831274..1832494	-	1221	WP_047526928.1	restriction endonuclease subunit S	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Hok/gef cell toxic protein (6-47)

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3554.32 Da
• Isoelectric Point: 10.4449

>T38110 WP_001801861.1 NZ_AP024200:1828861-1828956 [Staphylococcus argenteus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Nucleotide

• Length: 96 bp

>T38110 NZ_AP024200:1828861-1828956 [Staphylococcus argenteus]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin

Nucleotide

• Length: 58 bp

>AT38110 NZ_AP024200:c1829041-1828984 [Staphylococcus argenteus]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin