Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprG2-SprA2AS/-
Location 984065..984282 Replicon chromosome
Accession NZ_AP024200
Organism Staphylococcus argenteus strain Tokyo13064

Toxin (Protein)


Gene name SprG2 Uniprot ID -
Locus tag JN157_RS04650 Protein ID WP_014373809.1
Coordinates 984065..984172 (+) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 984167..984282 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JN157_RS04625 980744..981313 - 570 WP_000287261.1 competence protein ComK -
JN157_RS04630 981523..981741 + 219 WP_000876831.1 IDEAL domain-containing protein -
JN157_RS04635 981822..982808 - 987 WP_047526294.1 lipoate--protein ligase -
JN157_RS04640 983003..983179 + 177 WP_000214898.1 YkvS family protein -
JN157_RS04645 983194..983796 + 603 WP_031787353.1 CPBP family intramembrane metalloprotease -
JN157_RS04650 984065..984172 + 108 WP_014373809.1 putative holin-like toxin Toxin
- 984167..984282 - 116 - - Antitoxin
JN157_RS04655 984808..985092 + 285 WP_000790905.1 lactococcin 972 family bacteriocin -
JN157_RS04660 985136..987100 + 1965 WP_047526299.1 bacteriocin-associated integral membrane family protein -
JN157_RS04665 987103..987423 + 321 WP_047526301.1 YxeA family protein -
JN157_RS04670 987420..988061 + 642 WP_047526302.1 ABC transporter ATP-binding protein -
JN157_RS04675 988149..988409 - 261 WP_169929182.1 hypothetical protein -
JN157_RS04680 988724..989011 + 288 WP_000410715.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Small toxic protein BsrE-like

(3-35)


Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 3815.72 Da        Isoelectric Point: 10.8004

>T38108 WP_014373809.1 NZ_AP024200:984065-984172 [Staphylococcus argenteus]
VISIANALHLMLSFGMFIVTFIGIVVAIINLNNKK

Download         Length: 108 bp

>T38108 NZ_AP024200:984065-984172 [Staphylococcus argenteus]
GTGATATCTATTGCAAACGCATTACATTTAATGTTAAGTTTCGGTATGTTTATCGTAACTTTCATTGGTATAGTAGTCGC
AATAATTAATTTAAACAATAAAAAATAA

Antitoxin


Download         Length: 116 bp

>AT38108 NZ_AP024200:c984282-984167 [Staphylococcus argenteus]
GTAAAAAGACGACATGCAGGAACATGTCGCCTATTGAGCCCGTTAAAAAGACGGTGACTAAATGAGATTTTCTTTAACCA
TCATTCTTTGTCAAAGTTATGAAATGATGGTTATTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References