Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2236373..2236589 Replicon chromosome
Accession NZ_AP024170
Organism Staphylococcus aureus strain 834

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag SA834_RS11140 Protein ID WP_001802298.1
Coordinates 2236485..2236589 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF1
Locus tag -
Coordinates 2236373..2236428 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
SA834_RS11120 2232579..2233244 - 666 WP_001024095.1 SDR family oxidoreductase -
SA834_RS11125 2233396..2233716 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
SA834_RS11130 2233718..2234695 + 978 WP_000019734.1 CDF family zinc efflux transporter CzrB -
SA834_RS11135 2234961..2236052 + 1092 WP_000495669.1 hypothetical protein -
- 2236373..2236428 + 56 - - Antitoxin
SA834_RS11140 2236485..2236589 - 105 WP_001802298.1 hypothetical protein Toxin
SA834_RS11145 2237106..2237276 + 171 WP_001792292.1 transposase -
SA834_RS11150 2237269..2237427 + 159 WP_001792784.1 hypothetical protein -
SA834_RS11155 2238085..2238942 - 858 WP_000370925.1 Cof-type HAD-IIB family hydrolase -
SA834_RS11160 2239010..2239792 - 783 WP_000908182.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T38076 WP_001802298.1 NZ_AP024170:c2236589-2236485 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T38076 NZ_AP024170:c2236589-2236485 [Staphylococcus aureus]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTGATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin


Download         Length: 56 bp

>AT38076 NZ_AP024170:2236373-2236428 [Staphylococcus aureus]
AAAAAGGGCAACACTCGGAAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References