Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-RelB
Location 13398..13939 Replicon plasmid pAACEN2
Accession NZ_AP023412
Organism Acetobacter aceti NBRC 14818

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag EMQ_RS16895 Protein ID WP_010668420.1
Coordinates 13398..13667 (-) Length 90 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID G2I8S6
Locus tag EMQ_RS16900 Protein ID WP_010668421.1
Coordinates 13664..13939 (-) Length 92 a.a.

Genomic Context

EMQ_RS16875EMQ_RS16880EMQ_RS16925EMQ_RS16930EMQ_RS16870EMQ_RS16885EMQ_RS16890EMQ_RS16895EMQ_RS16900EMQ_RS16905EMQ_RS16910EMQ_RS16915EMQ_RS16920
Location: 11565..12113 (549 bp)
Type: Others
Protein ID: WP_035346056.1
Location: 12367..12837 (471 bp)
Type: Others
Protein ID: Protein_17
Location: 18143..18502 (360 bp)
Type: Others
Protein ID: WP_010665981.1
Location: 18567..18806 (240 bp)
Type: Others
Protein ID: WP_010665982.1
Location: 9247..10773 (1527 bp)
Type: Others
Protein ID: WP_010666062.1
Location: 12898..13062 (165 bp)
Type: Others
Protein ID: Protein_18
Location: 13041..13397 (357 bp)
Type: Others
Protein ID: WP_010668419.1
Location: 13398..13667 (270 bp)
Type: Toxin
Protein ID: WP_010668420.1
Location: 13664..13939 (276 bp)
Type: Antitoxin
Protein ID: WP_010668421.1
Location: 14165..14302 (138 bp)
Type: Others
Protein ID: WP_010668422.1
Location: 14328..14720 (393 bp)
Type: Others
Protein ID: WP_010668423.1
Location: 14717..14911 (195 bp)
Type: Others
Protein ID: WP_010668424.1
Location: 14966..18046 (3081 bp)
Type: Others
Protein ID: WP_018308595.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
EMQ_RS168709247..10773-1527WP_010666062.1hypothetical protein-
EMQ_RS1687511565..12113+549WP_035346056.1helix-turn-helix domain-containing protein-
EMQ_RS1688012367..12837+471Protein_17transposase-
EMQ_RS1688512898..13062-165Protein_18DUF4158 domain-containing protein-
EMQ_RS1689013041..13397-357WP_010668419.1hypothetical protein-
EMQ_RS1689513398..13667-270WP_010668420.1Txe/YoeB family addiction module toxinToxin
EMQ_RS1690013664..13939-276WP_010668421.1type II toxin-antitoxin system prevent-host-death family antitoxinAntitoxin
EMQ_RS1690514165..14302-138WP_010668422.1hypothetical protein-
EMQ_RS1691014328..14720-393WP_010668423.1PIN domain nuclease-
EMQ_RS1691514717..14911-195WP_010668424.1type II toxin-antitoxin system VapB family antitoxin-
EMQ_RS1692014966..18046-3081WP_018308595.1Ti-type conjugative transfer relaxase TraA-
EMQ_RS1692518143..18502+360WP_010665981.1conjugal transfer protein TraD-
EMQ_RS1693018567..18806+240WP_010665982.1conjugal transfer protein TraD-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
-insideNon-Mobilizable plasmid--1..2575525755


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 90 a.a.        Molecular weight: 13263.91 Da        Isoelectric Point: 5.5500

>T37695 WP_010668420.1 NZ_AP023412:c13667-13398 [Acetobacter aceti NBRC 14818]
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF
FFFFFFFFFF

Download         Length: 270 bp

>T37695 NZ_AP023412:c13667-13398 [Acetobacter aceti NBRC 14818]
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTT

Antitoxin


Download         Length: 92 a.a.        Molecular weight: 13558.26 Da        Isoelectric Point: 5.5500

>AT37695 WP_010668421.1 NZ_AP023412:c13939-13664 [Acetobacter aceti NBRC 14818]
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF
FFFFFFFFFFFF

Download         Length: 276 bp

>AT37695 NZ_AP023412:c13939-13664 [Acetobacter aceti NBRC 14818]
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
AlphaFold DBA0A149R124

References