Detailed information of TA system TA037695

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): yefM-yoeB (relBE)/YoeB-RelB
• Location: 13398..13939
• Replicon: plasmid pAACEN2
• Accession: NZ_AP023412
• Organism: Acetobacter aceti NBRC 14818

Toxin (Protein)

• Gene name: yoeB
• Uniprot ID: -
• Locus tag: EMQ_RS16895
• Protein ID: WP_010668420.1
• Coordinates: 13398..13667 (-)
• Length: 90 a.a.

Antitoxin (Protein)

• Gene name: yefM
• Uniprot ID: G2I8S6
• Locus tag: EMQ_RS16900
• Protein ID: WP_010668421.1
• Coordinates: 13664..13939 (-)
• Length: 92 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
EMQ_RS16870	9247..10773	-	1527	WP_010666062.1	hypothetical protein	-
EMQ_RS16875	11565..12113	+	549	WP_035346056.1	helix-turn-helix domain-containing protein	-
EMQ_RS16880	12367..12837	+	471	Protein_17	transposase	-
EMQ_RS16885	12898..13062	-	165	Protein_18	DUF4158 domain-containing protein	-
EMQ_RS16890	13041..13397	-	357	WP_010668419.1	hypothetical protein	-
EMQ_RS16895	13398..13667	-	270	WP_010668420.1	Txe/YoeB family addiction module toxin	Toxin
EMQ_RS16900	13664..13939	-	276	WP_010668421.1	type II toxin-antitoxin system prevent-host-death family antitoxin	Antitoxin
EMQ_RS16905	14165..14302	-	138	WP_010668422.1	hypothetical protein	-
EMQ_RS16910	14328..14720	-	393	WP_010668423.1	PIN domain nuclease	-
EMQ_RS16915	14717..14911	-	195	WP_010668424.1	type II toxin-antitoxin system VapB family antitoxin	-
EMQ_RS16920	14966..18046	-	3081	WP_018308595.1	Ti-type conjugative transfer relaxase TraA	-
EMQ_RS16925	18143..18502	+	360	WP_010665981.1	conjugal transfer protein TraD	-
EMQ_RS16930	18567..18806	+	240	WP_010665982.1	conjugal transfer protein TraD	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Non-Mobilizable plasmid	-	-	1..25755	25755

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 90 a.a.
• Molecular weight: 13263.91 Da
• Isoelectric Point: 5.5500

>T37695 WP_010668420.1 NZ_AP023412:c13667-13398 [Acetobacter aceti NBRC 14818]
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF
FFFFFFFFFF

Nucleotide

• Length: 270 bp

>T37695 NZ_AP023412:c13667-13398 [Acetobacter aceti NBRC 14818]
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTT

Antitoxin

Protein

• Length: 92 a.a.
• Molecular weight: 13558.26 Da
• Isoelectric Point: 5.5500

>AT37695 WP_010668421.1 NZ_AP023412:c13939-13664 [Acetobacter aceti NBRC 14818]
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF
FFFFFFFFFFFF

Nucleotide

• Length: 276 bp

>AT37695 NZ_AP023412:c13939-13664 [Acetobacter aceti NBRC 14818]
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT

Structures

Antitoxin

• AlphaFold DB: A0A149R124