Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mqsRA (relBE)/MqsR-MqsA
Location 2143988..2144687 Replicon chromosome
Accession NZ_AP023348
Organism Pseudomonas sp. RtIB026

Toxin (Protein)


Gene name mqsR Uniprot ID -
Locus tag PRtIB026_RS09725 Protein ID WP_203651799.1
Coordinates 2143988..2144284 (+) Length 99 a.a.

Antitoxin (Protein)


Gene name mqsA Uniprot ID -
Locus tag PRtIB026_RS09730 Protein ID WP_203651800.1
Coordinates 2144286..2144687 (+) Length 134 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PRtIB026_RS09705 2139987..2141165 - 1179 WP_203651797.1 efflux RND transporter periplasmic adaptor subunit -
PRtIB026_RS09710 2141382..2141858 + 477 WP_186732870.1 sigma-70 family RNA polymerase sigma factor -
PRtIB026_RS09715 2142031..2142515 + 485 Protein_1896 histidine kinase -
PRtIB026_RS09720 2142569..2143893 + 1325 Protein_1897 MFS transporter -
PRtIB026_RS09725 2143988..2144284 + 297 WP_203651799.1 type II toxin-antitoxin system MqsR family toxin Toxin
PRtIB026_RS09730 2144286..2144687 + 402 WP_203651800.1 type II toxin-antitoxin system MqsA family antitoxin Antitoxin
PRtIB026_RS09735 2144837..2146486 + 1650 WP_203651801.1 hypothetical protein -
PRtIB026_RS09740 2146550..2148214 - 1665 WP_203651802.1 electron transfer flavoprotein-ubiquinone oxidoreductase -
PRtIB026_RS09745 2148757..2149506 + 750 WP_028692905.1 electron transfer flavoprotein subunit beta/FixA family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase toxin MqsR

(5-97)

Antitoxin

Cro/C1-type helix-turn-helix domain

(74-127)


Sequences

Toxin        


Download         Length: 99 a.a.        Molecular weight: 11578.46 Da        Isoelectric Point: 9.5783

>T37648 WP_203651799.1 NZ_AP023348:2143988-2144284 [Pseudomonas sp. RtIB026]
MEKRTPHCPLERVRMLMSQGRVRPTRTAIQDCDALGLSPRQMLEVVRGLSAHDFYKSMTTYHDHRIWQDVYRPRTVFGDL
YIKLTVVDDVLIVSFKER

Download         Length: 297 bp

>T37648 NZ_AP023348:2143988-2144284 [Pseudomonas sp. RtIB026]
ATGGAAAAGAGAACGCCGCACTGCCCGCTGGAAAGGGTGCGAATGTTGATGAGCCAGGGCCGGGTCAGGCCCACCCGGAC
AGCTATCCAGGACTGTGATGCGCTCGGGCTGAGCCCTCGCCAGATGCTTGAAGTCGTTCGAGGCTTGTCGGCACACGATT
TCTACAAAAGCATGACGACCTATCACGATCATCGGATCTGGCAGGATGTCTATCGTCCCCGAACCGTCTTTGGCGATCTC
TACATCAAGCTGACGGTGGTCGATGACGTGCTGATCGTGTCATTCAAGGAGCGTTGA

Antitoxin


Download         Length: 134 a.a.        Molecular weight: 14682.85 Da        Isoelectric Point: 5.7576

>AT37648 WP_203651800.1 NZ_AP023348:2144286-2144687 [Pseudomonas sp. RtIB026]
MKCPVCGGAELVAQAQDMPYRYNGHSTVIRDVFGDYCPVCGEAVLSMAEAERLGDLMLAFKRQVNAAAVDPAFIASVRRK
FDLDQREAGEIFGGGVNAFSRYENGKTQPPVALIKLFKLLDRHPELFEEVRTA

Download         Length: 402 bp

>AT37648 NZ_AP023348:2144286-2144687 [Pseudomonas sp. RtIB026]
ATGAAGTGTCCCGTGTGTGGTGGTGCTGAGCTGGTCGCCCAGGCTCAGGACATGCCTTATCGATACAATGGCCATTCGAC
GGTGATCCGTGATGTCTTCGGCGATTATTGCCCTGTTTGCGGCGAGGCGGTGCTGAGCATGGCTGAAGCTGAGCGCCTCG
GTGATCTGATGCTGGCCTTCAAGCGACAGGTCAATGCCGCCGCTGTCGACCCTGCCTTCATTGCCAGCGTTCGGCGCAAA
TTCGACCTCGATCAGCGTGAGGCGGGCGAAATCTTTGGCGGCGGGGTCAATGCCTTTTCCCGTTACGAGAACGGCAAGAC
CCAACCACCGGTCGCACTGATCAAGCTGTTCAAGCTCCTGGATCGTCATCCGGAACTGTTCGAGGAAGTCAGGACTGCCT
GA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References