Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) prlF-yhaV (relBE)/YhaV-PrlF
Location 1181159..1181979 Replicon chromosome
Accession NZ_AP023348
Organism Pseudomonas sp. RtIB026

Toxin (Protein)


Gene name yhaV Uniprot ID -
Locus tag PRtIB026_RS05365 Protein ID WP_203650632.1
Coordinates 1181159..1181656 (-) Length 166 a.a.

Antitoxin (Protein)


Gene name prlF Uniprot ID A0A8I0D4S5
Locus tag PRtIB026_RS05370 Protein ID WP_050704328.1
Coordinates 1181653..1181979 (-) Length 109 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PRtIB026_RS05345 1176350..1177879 + 1530 WP_203650626.1 efflux transporter outer membrane subunit -
PRtIB026_RS05350 1177876..1180053 + 2178 WP_203650628.1 FUSC family protein -
PRtIB026_RS05355 1180043..1180243 + 201 WP_028689551.1 DUF1656 domain-containing protein -
PRtIB026_RS05360 1180254..1181114 + 861 WP_203650630.1 HlyD family secretion protein -
PRtIB026_RS05365 1181159..1181656 - 498 WP_203650632.1 type II toxin-antitoxin system YhaV family toxin Toxin
PRtIB026_RS05370 1181653..1181979 - 327 WP_050704328.1 type II toxin-antitoxin system PrlF family antitoxin Antitoxin
PRtIB026_RS05375 1182089..1182535 - 447 WP_203650634.1 universal stress protein -
PRtIB026_RS05380 1182784..1183719 + 936 WP_203650636.1 LysR family transcriptional regulator -
PRtIB026_RS05385 1183957..1185480 + 1524 WP_203650638.1 MFS transporter -
PRtIB026_RS05390 1185508..1186569 + 1062 WP_203650640.1 HlyD family secretion protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin endonuclease, YhaV

(16-152)

Antitoxin

PrlF antitoxin

(8-106)


Sequences

Toxin        


Download         Length: 166 a.a.        Molecular weight: 19055.76 Da        Isoelectric Point: 10.0755

>T37646 WP_203650632.1 NZ_AP023348:c1181656-1181159 [Pseudomonas sp. RtIB026]
MTETRRKPLCVHGWSVFAHPLFLDKLEALIDEVEVLQKKDPVGYVKKNAAKRLKAVRRLAFDVIAQAPGNADHRMGGTLG
AEHKHWFRAKFFQQYRLFYRYHASSKIIVLAWVNDDDSKHAYESSDDAYRVFRRMLGSGHPPDDWDQLLQEATAATARFN
ATLKR

Download         Length: 498 bp

>T37646 NZ_AP023348:c1181656-1181159 [Pseudomonas sp. RtIB026]
ATGACTGAAACGAGGCGCAAACCTCTTTGCGTGCATGGCTGGAGCGTGTTCGCCCACCCCCTCTTTCTCGACAAACTGGA
GGCACTCATCGATGAAGTCGAAGTGCTTCAGAAGAAGGATCCGGTCGGCTACGTAAAGAAAAATGCGGCAAAACGATTGA
AGGCCGTCAGACGCTTGGCCTTCGACGTCATTGCCCAGGCGCCTGGCAACGCTGACCATCGAATGGGCGGCACACTGGGC
GCGGAACACAAGCACTGGTTTCGTGCAAAGTTCTTCCAGCAATACCGCTTGTTTTATCGCTATCACGCCTCCAGCAAGAT
CATCGTGTTGGCGTGGGTGAACGATGACGACAGCAAACACGCTTACGAAAGCAGTGACGATGCCTACAGAGTGTTCCGTC
GCATGCTGGGCAGCGGACACCCTCCTGATGACTGGGACCAACTGTTGCAGGAAGCGACCGCGGCAACAGCTCGATTCAAC
GCCACCCTCAAGCGCTGA

Antitoxin


Download         Length: 109 a.a.        Molecular weight: 11997.46 Da        Isoelectric Point: 4.2522

>AT37646 WP_050704328.1 NZ_AP023348:c1181979-1181653 [Pseudomonas sp. RtIB026]
MATTFEAESTLTERYQTTVPETVRRALGLKKRDKIHYSIRPDGAVILTRAETAEEDPAVGQFLDFLARDIATNPQRLKVV
DAELVARLDALVGDVEIDLDQPLSADDE

Download         Length: 327 bp

>AT37646 NZ_AP023348:c1181979-1181653 [Pseudomonas sp. RtIB026]
ATGGCCACTACCTTCGAAGCCGAGTCGACCCTGACCGAGCGCTACCAGACGACGGTCCCCGAAACCGTTCGCCGTGCCTT
GGGCCTGAAAAAACGTGACAAGATTCACTACTCGATCCGCCCTGACGGAGCGGTAATACTGACCCGCGCAGAGACAGCCG
AGGAAGACCCCGCCGTGGGGCAGTTCCTGGATTTCCTGGCCCGGGATATCGCCACGAATCCGCAACGATTGAAGGTTGTC
GATGCAGAGCTCGTCGCTCGCCTGGATGCACTGGTGGGCGACGTTGAAATCGATCTCGATCAACCTCTCTCGGCGGATGA
TGAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References