36779

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) HipBST/HipA(toxin)
Location 2262628..2263982 Replicon chromosome
Accession NZ_AP023184
Organism Buttiauxella agrestis strain DSM 9389

Toxin (Protein)


Gene name HipT Uniprot ID -
Locus tag BADSM9389_RS10635 Protein ID WP_172894197.1
Coordinates 2262628..2263665 (-) Length 346 a.a.

Antitoxin (Protein)


Gene name HipS Uniprot ID -
Locus tag BADSM9389_RS10640 Protein ID WP_172894199.1
Coordinates 2263668..2263982 (-) Length 105 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BADSM9389_RS10600 2257740..2258069 - 330 WP_034495476.1 DUF3302 domain-containing protein -
BADSM9389_RS10605 2258301..2258474 + 174 WP_115628548.1 GhoT/OrtT family toxin -
BADSM9389_RS10610 2258520..2258849 + 330 WP_172894188.1 N(4)-acetylcytidine aminohydrolase -
BADSM9389_RS10615 2258918..2259145 - 228 WP_115628550.1 DUF465 domain-containing protein -
BADSM9389_RS10620 2259412..2260173 + 762 WP_172894190.1 siderophore-interacting protein -
BADSM9389_RS10625 2260184..2260762 + 579 WP_172894192.1 PadR family transcriptional regulator -
BADSM9389_RS10630 2260849..2262513 + 1665 WP_172894194.1 methyl-accepting chemotaxis protein -
BADSM9389_RS10635 2262628..2263665 - 1038 WP_172894197.1 HipA domain-containing protein Toxin
BADSM9389_RS10640 2263668..2263982 - 315 WP_172894199.1 HipA N-terminal domain-containing protein Antitoxin
BADSM9389_RS10645 2263967..2264290 - 324 WP_197969186.1 helix-turn-helix domain-containing protein -
BADSM9389_RS10650 2264602..2265624 + 1023 WP_172894200.1 MsnO8 family LLM class oxidoreductase -
BADSM9389_RS10655 2265635..2266756 + 1122 WP_172894202.1 amidohydrolase -
BADSM9389_RS10660 2266774..2268084 + 1311 WP_172894204.1 LLM class flavin-dependent oxidoreductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

HipA-like, C-terminal

(56-302)

Antitoxin

HipA, N-terminal subdomain 1

(6-98)


Sequences

Toxin        


Download         Length: 346 a.a.        Molecular weight: 38868.51 Da        Isoelectric Point: 6.5748

>T36779 WP_172894197.1 NZ_AP023184:c2263665-2262628 [Buttiauxella agrestis]
MRCHILLTPLVQAKVQESGYSSKGLKYLTGSGKVNPQLSFTRNEFIHELPKAQRGMSISGYQPKLQMVVRDGEFAVVEHQ
GEYILKPSPAEFPHLAENEHATMRLMSRLGFDVPPHGLVSFAREDNQTTPELAFVIRRFDRDIQTGAAIHQEQLDAAMNV
GEKYGKTGSDGKQNVSYQQLAEFLTQHVNSNLAFKIDLFRRIAYAYLLGNNDMHLRNFGLIHPRIGEPTLSPVYDFVSVA
PYPAIFSSGFMALPLLSCEEGDRELAPGFKTAYGEYLGMDFRELGLAIGLTDKLIVKLLSDLQKESRIVEAVYRDSFMPP
EAIDATLRCYHQRLDRLMRLDEAPL

Download         Length: 1038 bp

>T36779 NZ_AP023184:c2263665-2262628 [Buttiauxella agrestis]
ATGCGCTGCCATATTCTTTTGACGCCGCTGGTGCAGGCTAAAGTGCAGGAGTCCGGCTATTCATCCAAAGGGCTGAAGTA
CCTGACTGGCTCTGGCAAAGTGAACCCGCAGCTGAGTTTTACACGCAATGAATTTATACATGAATTGCCCAAAGCCCAGC
GCGGAATGAGCATCTCCGGCTATCAGCCTAAACTGCAAATGGTGGTGCGCGACGGTGAATTTGCCGTGGTCGAACACCAG
GGTGAATACATTCTTAAACCGTCTCCGGCAGAATTCCCCCATCTGGCGGAAAACGAACACGCCACCATGCGGCTTATGTC
GCGGCTGGGATTTGACGTGCCGCCTCATGGGCTGGTGAGTTTTGCGCGTGAAGACAACCAAACCACGCCAGAACTGGCCT
TTGTGATCCGCCGCTTTGACAGAGACATTCAAACCGGGGCCGCGATCCACCAGGAGCAACTGGATGCGGCGATGAATGTC
GGCGAAAAGTACGGAAAAACCGGTAGCGACGGCAAACAGAACGTCAGCTATCAGCAATTAGCCGAGTTTCTGACGCAACA
TGTGAACAGCAACCTCGCCTTTAAAATCGACCTGTTCCGGCGCATTGCTTACGCGTATCTGCTGGGCAATAACGATATGC
ATCTGCGCAATTTCGGGCTGATACACCCGCGCATCGGCGAGCCGACATTATCGCCGGTTTACGATTTTGTCTCGGTTGCG
CCCTATCCGGCCATTTTTAGCTCAGGGTTTATGGCGCTGCCGTTACTGAGTTGCGAGGAAGGCGACCGCGAGCTAGCACC
AGGTTTTAAAACTGCATATGGTGAATATCTTGGTATGGATTTCCGGGAACTCGGCCTGGCGATAGGATTGACCGACAAAC
TTATCGTGAAGTTATTGAGTGATTTGCAAAAAGAGAGCCGCATTGTGGAAGCGGTATATCGTGATTCGTTTATGCCACCC
GAGGCGATTGACGCCACGCTGCGTTGTTACCATCAGCGGCTGGACAGGTTGATGCGCCTGGACGAAGCACCGTTGTGA

Antitoxin


Download         Length: 105 a.a.        Molecular weight: 11834.53 Da        Isoelectric Point: 5.0760

>AT36779 WP_172894199.1 NZ_AP023184:c2263982-2263668 [Buttiauxella agrestis]
MRRRVEVWLYGEPVGELRQDDGGFAFSYRADYIGPPLSLSLPVRVGHFQSPTLPPFFASLAPEGWLKMRYSQLQQRDEHD
LLGMLIDNGKNLIGAVQLVSMQEE

Download         Length: 315 bp

>AT36779 NZ_AP023184:c2263982-2263668 [Buttiauxella agrestis]
ATGCGCCGCCGTGTAGAGGTCTGGTTATACGGTGAGCCGGTGGGTGAGCTGCGCCAGGATGACGGCGGTTTTGCGTTTAG
TTATCGCGCCGATTATATCGGCCCGCCGCTGTCGCTCAGTTTACCGGTGCGTGTGGGTCATTTTCAAAGCCCGACACTGC
CGCCCTTTTTTGCCTCGCTGGCACCGGAAGGCTGGCTGAAAATGCGCTACAGCCAATTACAGCAGCGCGACGAGCATGAC
CTTCTCGGGATGCTTATCGACAACGGTAAAAACCTGATTGGTGCGGTGCAACTGGTCAGCATGCAGGAGGAGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References