Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/HTH(antitoxin)
Location 1798179..1798784 Replicon chromosome
Accession NZ_AP023184
Organism Buttiauxella agrestis strain DSM 9389

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag BADSM9389_RS08430 Protein ID WP_172896108.1
Coordinates 1798473..1798784 (-) Length 104 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag BADSM9389_RS08425 Protein ID WP_172893840.1
Coordinates 1798179..1798472 (-) Length 98 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BADSM9389_RS08405 1794430..1795383 + 954 WP_034496139.1 ABC transporter permease -
BADSM9389_RS08410 1795388..1796233 + 846 WP_115628091.1 ABC transporter permease -
BADSM9389_RS08415 1796226..1797209 + 984 WP_172893838.1 ABC transporter ATP-binding protein -
BADSM9389_RS08420 1797196..1798182 + 987 WP_172893839.1 ABC transporter ATP-binding protein -
BADSM9389_RS08425 1798179..1798472 - 294 WP_172893840.1 helix-turn-helix domain-containing protein Antitoxin
BADSM9389_RS08430 1798473..1798784 - 312 WP_172896108.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
BADSM9389_RS08435 1798993..1799244 + 252 WP_034496127.1 DUF2766 domain-containing protein -
BADSM9389_RS08440 1799303..1800646 - 1344 WP_172893841.1 anaerobic C4-dicarboxylate transporter -
BADSM9389_RS08445 1800792..1802810 - 2019 WP_172893842.1 heparinase II/III family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Cro/C1-type helix-turn-helix domain

(36-87)


Sequences

Toxin        


Download         Length: 104 a.a.        Molecular weight: 12025.96 Da        Isoelectric Point: 9.5486

>T36770 WP_172896108.1 NZ_AP023184:c1798784-1798473 [Buttiauxella agrestis]
MLFIETPIFTEDVSALLTDEEYRLFQVFLTCSPESGDVIPHSGGLRKVRWLAKNKGKRGGVRVIYFHKNADSIIRLLLIY
PKGVKDDLNEAEKRFLRQMNERW

Download         Length: 312 bp

>T36770 NZ_AP023184:c1798784-1798473 [Buttiauxella agrestis]
ATGCTTTTTATTGAAACGCCCATTTTTACAGAGGATGTCAGTGCCCTGCTCACGGATGAAGAATACAGGCTGTTTCAGGT
ATTCCTCACCTGTTCACCGGAAAGTGGCGATGTGATTCCTCATTCTGGCGGTCTGCGTAAGGTACGCTGGCTGGCGAAAA
ACAAAGGAAAGCGAGGTGGCGTCAGAGTCATCTATTTCCATAAGAACGCGGATAGCATCATCAGACTGTTGCTGATTTAT
CCGAAAGGGGTCAAAGACGATCTGAATGAGGCCGAAAAGCGTTTTTTGCGGCAAATGAACGAGAGGTGGTAA

Antitoxin


Download         Length: 98 a.a.        Molecular weight: 10630.31 Da        Isoelectric Point: 10.1888

>AT36770 WP_172893840.1 NZ_AP023184:c1798472-1798179 [Buttiauxella agrestis]
MDKLLFERLSKSMTQMNEIVEGQCAASRVTEVTATQVKAIRQATGLSQAGFARLISVSVDTLKNWEQGRREPTGPAKALL
RAIENDPVHVILALAPR

Download         Length: 294 bp

>AT36770 NZ_AP023184:c1798472-1798179 [Buttiauxella agrestis]
ATGGATAAGCTATTATTCGAGCGTCTGTCCAAAAGCATGACGCAAATGAATGAGATTGTAGAAGGTCAGTGCGCAGCCTC
TCGTGTGACGGAAGTCACTGCAACTCAGGTCAAAGCGATTCGCCAGGCAACAGGATTGTCACAAGCCGGTTTTGCCAGGC
TTATTTCCGTAAGTGTAGATACGTTAAAAAATTGGGAACAGGGCCGCCGCGAACCGACAGGCCCTGCTAAAGCATTATTG
CGTGCGATAGAGAATGACCCGGTTCATGTCATTCTCGCACTGGCGCCACGCTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References