Detailed information of TA system TA036731

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): mqsRA (relBE)/MqsR-MqsA
• Location: 4909573..4910273
• Replicon: chromosome
• Accession: NZ_AP023081
• Organism: Pseudomonas solani strain Sm006

Toxin (Protein)

• Gene name: mqsR
• Uniprot ID: -
• Locus tag: PSm6_RS22500
• Protein ID: WP_265170557.1
• Coordinates: 4909977..4910273 (-)
• Length: 99 a.a.

Antitoxin (Protein)

• Gene name: mqsA
• Uniprot ID: -
• Locus tag: PSm6_RS22495
• Protein ID: WP_165666555.1
• Coordinates: 4909573..4909974 (-)
• Length: 134 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
PSm6_RS22465	4905245..4905712	-	468	Protein_4420	GrpB family protein	-
PSm6_RS22470 (PSm6_45170)	4905876..4906607	-	732	WP_265168288.1	hypothetical protein	-
PSm6_RS22475 (PSm6_45180)	4906604..4907083	-	480	WP_265168289.1	hypothetical protein	-
PSm6_RS22480 (PSm6_45190)	4907344..4907583	-	240	WP_265168290.1	hypothetical protein	-
PSm6_RS22485 (PSm6_45200)	4907673..4907930	-	258	WP_173180033.1	hypothetical protein	-
PSm6_RS22490	4909154..4909303	-	150	Protein_4425	RHS repeat-associated core domain-containing protein	-
PSm6_RS22495 (PSm6_45230)	4909573..4909974	-	402	WP_165666555.1	type II toxin-antitoxin system MqsA family antitoxin	Antitoxin
PSm6_RS22500 (PSm6_45240)	4909977..4910273	-	297	WP_265170557.1	type II toxin-antitoxin system MqsR family toxin	Toxin
PSm6_RS22505 (PSm6_45250)	4910347..4911300	-	954	WP_265168291.1	tyrosine-type recombinase/integrase	-
PSm6_RS22510 (PSm6_45260)	4911290..4912144	-	855	WP_265168292.1	hypothetical protein	-
PSm6_RS22515 (PSm6_45270)	4912147..4912896	-	750	WP_265168293.1	IS21-like element helper ATPase IstB	-
PSm6_RS22520 (PSm6_45280)	4912889..4914433	-	1545	WP_265168294.1	IS21 family transposase	-
PSm6_RS22525 (PSm6_45290)	4914701..4915003	-	303	WP_265168295.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Genomic island	-	-	4900816..4938879	38063

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• mRNA interferase toxin MqsR (5-97)

Antitoxin

• Antitoxin MqsA/HigA-2 (1-131)

Sequences

Toxin

Protein

• Length: 99 a.a.
• Molecular weight: 10691.35 Da
• Isoelectric Point: 5.5873

>T36731 WP_265170557.1 NZ_AP023081:c4910273-4909977 [Pseudomonas solani]
MEKRTPHCKLADVKALVEAGKVRSTMSALTGGAALGFDFEGIVGVVMALAPADFYKSMTTHADHTVWQDVYRTNTEAGEV
YLKLTVIDDVLIVSFKEL

Nucleotide

• Length: 297 bp

>T36731 NZ_AP023081:c4910273-4909977 [Pseudomonas solani]
ATGGAAAAAAGAACTCCGCACTGCAAGCTAGCGGACGTCAAAGCCTTGGTCGAAGCAGGAAAAGTGCGCTCCACCATGTC
CGCCCTGACTGGAGGAGCGGCGTTGGGGTTCGACTTCGAGGGAATCGTCGGCGTTGTCATGGCGCTGGCCCCGGCAGACT
TCTACAAAAGCATGACCACGCACGCCGACCACACGGTCTGGCAAGACGTGTACCGGACAAACACGGAAGCCGGAGAGGTC
TACCTGAAACTCACGGTCATTGATGACGTGCTCATCGTGTCCTTCAAGGAGCTATGA

Antitoxin

Protein

• Length: 134 a.a.
• Molecular weight: 14336.42 Da
• Isoelectric Point: 7.0826

>AT36731 WP_165666555.1 NZ_AP023081:c4909974-4909573 [Pseudomonas solani]
MKCPSCAAAELVHDTRDLPYTYKNESTTIPAVTGDFCPACGEAVLDAGESARVSTAMLGFNKQVNASIVDPSFIANVRKK
LALDQREAAEIFGGGVNAFSRYENGKTKPPLALVKLLKVLDRHPELLNEVRTA

Nucleotide

• Length: 402 bp

>AT36731 NZ_AP023081:c4909974-4909573 [Pseudomonas solani]
ATGAAATGTCCATCCTGCGCAGCGGCGGAACTGGTGCACGACACCCGCGACCTGCCATACACCTACAAGAACGAGTCGAC
CACCATTCCAGCAGTAACCGGCGACTTCTGCCCGGCCTGTGGCGAGGCAGTTCTGGATGCAGGTGAGTCGGCCCGCGTCA
GCACGGCGATGCTGGGGTTTAACAAGCAGGTGAATGCTTCGATCGTTGACCCGAGCTTCATCGCCAACGTCCGCAAGAAG
CTCGCCCTCGACCAGCGTGAAGCGGCCGAGATTTTCGGCGGCGGCGTCAACGCGTTCTCGCGCTACGAGAACGGTAAGAC
CAAGCCGCCGCTGGCCCTGGTGAAACTGCTCAAGGTGCTTGATCGCCACCCTGAACTGCTAAACGAAGTCAGGACGGCCT
AG