Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/Txe-RelB
Location 1802937..1803442 Replicon chromosome
Accession NZ_AP023063
Organism Nitratiruptor sp. YY08-26

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag JG738_RS09675 Protein ID WP_201337690.1
Coordinates 1802937..1803197 (-) Length 87 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag JG738_RS09680 Protein ID WP_201337691.1
Coordinates 1803197..1803442 (-) Length 82 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JG738_RS09650 1799503..1800879 + 1377 WP_201337686.1 pyruvate kinase -
JG738_RS09655 1800901..1801329 + 429 WP_201337687.1 hypothetical protein -
JG738_RS09660 1801309..1801479 - 171 WP_201337688.1 hypothetical protein -
JG738_RS09665 1801482..1801838 - 357 WP_084274853.1 hypothetical protein -
JG738_RS09670 1801828..1802820 - 993 WP_201337689.1 Lrp/AsnC family transcriptional regulator -
JG738_RS09675 1802937..1803197 - 261 WP_201337690.1 Txe/YoeB family addiction module toxin Toxin
JG738_RS09680 1803197..1803442 - 246 WP_201337691.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
JG738_RS09685 1803575..1804144 + 570 WP_201337692.1 bifunctional precorrin-2 dehydrogenase/sirohydrochlorin ferrochelatase -
JG738_RS09690 1804147..1804518 + 372 WP_201337693.1 hypothetical protein -
JG738_RS09695 1804518..1805288 + 771 WP_201337694.1 endo alpha-1,4 polygalactosaminidase -
JG738_RS09700 1805267..1805755 - 489 WP_201337695.1 nitrous oxide reductase accessory protein NosL -
JG738_RS09705 1805767..1806594 - 828 WP_201337696.1 ABC transporter permease subunit -
JG738_RS09710 1806591..1807046 - 456 WP_201337697.1 nitrous oxide reductase accessory protein NosL -
JG738_RS09715 1807033..1807671 - 639 WP_201337698.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(6-85)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(3-70)


Sequences

Toxin        


Download         Length: 87 a.a.        Molecular weight: 10177.03 Da        Isoelectric Point: 10.1799

>T36702 WP_201337690.1 NZ_AP023063:c1803197-1802937 [Nitratiruptor sp. YY08-26]
MYKIVYTKQAVKDAKKIKEAGLKDKVLKLLSILENDPFANPPKYEKLVGDLKGAYSRRINIQHRLVYQVLEEEKTVKILR
MWTHYE

Download         Length: 261 bp

>T36702 NZ_AP023063:c1803197-1802937 [Nitratiruptor sp. YY08-26]
ATGTATAAAATTGTTTATACAAAACAGGCTGTGAAAGATGCAAAAAAGATTAAAGAAGCTGGTTTAAAAGATAAAGTTTT
AAAGTTGCTGAGTATTTTAGAAAACGATCCTTTTGCTAATCCTCCAAAATATGAAAAGTTGGTAGGAGATTTAAAAGGTG
CCTATAGCAGAAGAATAAACATACAACATAGATTAGTGTATCAAGTTTTGGAAGAAGAAAAAACTGTCAAAATTCTTAGA
ATGTGGACGCATTATGAATAG

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 9234.56 Da        Isoelectric Point: 4.6535

>AT36702 WP_201337691.1 NZ_AP023063:c1803442-1803197 [Nitratiruptor sp. YY08-26]
MTKIINVSKARDNLYKLIDETAESHEPILIKGKRNSAVLISEEDFRAIAETLYLTSIPGMRESIKEGLNTPIQECEDKLD
W

Download         Length: 246 bp

>AT36702 NZ_AP023063:c1803442-1803197 [Nitratiruptor sp. YY08-26]
ATGACAAAAATAATAAATGTCTCTAAGGCAAGAGACAATCTCTATAAGCTTATAGATGAGACTGCTGAAAGTCATGAGCC
TATTTTGATAAAAGGTAAAAGAAACAGTGCTGTATTAATAAGTGAAGAGGATTTTAGAGCAATTGCAGAGACACTTTATC
TTACTTCAATTCCTGGAATGAGAGAATCAATAAAAGAAGGATTAAATACCCCTATACAAGAGTGTGAAGATAAATTGGAC
TGGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References