Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/Txe-RelB
Location 1802932..1803437 Replicon chromosome
Accession NZ_AP023059
Organism Nitratiruptor sp. YY08-13

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag JG736_RS09665 Protein ID WP_201337690.1
Coordinates 1802932..1803192 (-) Length 87 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag JG736_RS09670 Protein ID WP_201337691.1
Coordinates 1803192..1803437 (-) Length 82 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JG736_RS09640 1799498..1800874 + 1377 WP_201337686.1 pyruvate kinase -
JG736_RS09645 1800896..1801324 + 429 WP_201337687.1 hypothetical protein -
JG736_RS09650 1801304..1801474 - 171 WP_201337688.1 hypothetical protein -
JG736_RS09655 1801477..1801833 - 357 WP_084274853.1 hypothetical protein -
JG736_RS09660 1801823..1802815 - 993 WP_201337689.1 Lrp/AsnC family transcriptional regulator -
JG736_RS09665 1802932..1803192 - 261 WP_201337690.1 Txe/YoeB family addiction module toxin Toxin
JG736_RS09670 1803192..1803437 - 246 WP_201337691.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
JG736_RS09675 1803570..1804139 + 570 WP_201337692.1 bifunctional precorrin-2 dehydrogenase/sirohydrochlorin ferrochelatase -
JG736_RS09680 1804142..1804513 + 372 WP_201337693.1 hypothetical protein -
JG736_RS09685 1804513..1805283 + 771 WP_201337694.1 endo alpha-1,4 polygalactosaminidase -
JG736_RS09690 1805262..1805750 - 489 WP_201337695.1 nitrous oxide reductase accessory protein NosL -
JG736_RS09695 1805762..1806589 - 828 WP_201337696.1 ABC transporter permease subunit -
JG736_RS09700 1806586..1807041 - 456 WP_201337697.1 nitrous oxide reductase accessory protein NosL -
JG736_RS09705 1807028..1807666 - 639 WP_201337698.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(6-85)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(3-70)


Sequences

Toxin        


Download         Length: 87 a.a.        Molecular weight: 10177.03 Da        Isoelectric Point: 10.1799

>T36698 WP_201337690.1 NZ_AP023059:c1803192-1802932 [Nitratiruptor sp. YY08-13]
MYKIVYTKQAVKDAKKIKEAGLKDKVLKLLSILENDPFANPPKYEKLVGDLKGAYSRRINIQHRLVYQVLEEEKTVKILR
MWTHYE

Download         Length: 261 bp

>T36698 NZ_AP023059:c1803192-1802932 [Nitratiruptor sp. YY08-13]
ATGTATAAAATTGTTTATACAAAACAGGCTGTGAAAGATGCAAAAAAGATTAAAGAAGCTGGTTTAAAAGATAAAGTTTT
AAAGTTGCTGAGTATTTTAGAAAACGATCCTTTTGCTAATCCTCCAAAATATGAAAAGTTGGTAGGAGATTTAAAAGGTG
CCTATAGCAGAAGAATAAACATACAACATAGATTAGTGTATCAAGTTTTGGAAGAAGAAAAAACTGTCAAAATTCTTAGA
ATGTGGACGCATTATGAATAG

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 9234.56 Da        Isoelectric Point: 4.6535

>AT36698 WP_201337691.1 NZ_AP023059:c1803437-1803192 [Nitratiruptor sp. YY08-13]
MTKIINVSKARDNLYKLIDETAESHEPILIKGKRNSAVLISEEDFRAIAETLYLTSIPGMRESIKEGLNTPIQECEDKLD
W

Download         Length: 246 bp

>AT36698 NZ_AP023059:c1803437-1803192 [Nitratiruptor sp. YY08-13]
ATGACAAAAATAATAAATGTCTCTAAGGCAAGAGACAATCTCTATAAGCTTATAGATGAGACTGCTGAAAGTCATGAGCC
TATTTTGATAAAAGGTAAAAGAAACAGTGCTGTATTAATAAGTGAAGAGGATTTTAGAGCAATTGCAGAGACACTTTATC
TTACTTCAATTCCTGGAATGAGAGAATCAATAAAAGAAGGATTAAATACCCCTATACAAGAGTGTGAAGATAAATTGGAC
TGGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References