Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2232530..2232747 Replicon chromosome
Accession NZ_AP023034
Organism Staphylococcus aureus strain TPS3156

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag HZ307_RS11160 Protein ID WP_001802298.1
Coordinates 2232643..2232747 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF4
Locus tag -
Coordinates 2232530..2232585 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HZ307_RS11140 2228667..2229332 - 666 WP_001024094.1 SDR family oxidoreductase -
HZ307_RS11145 2229484..2229804 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
HZ307_RS11150 2229806..2230786 + 981 WP_000019744.1 CDF family zinc efflux transporter CzrB -
HZ307_RS11155 2231052..2232143 + 1092 WP_000495671.1 lytic regulatory protein -
- 2232530..2232585 + 56 - - Antitoxin
HZ307_RS11160 2232643..2232747 - 105 WP_001802298.1 hypothetical protein Toxin
HZ307_RS11165 2232908..2233391 - 484 Protein_2158 recombinase family protein -
HZ307_RS11170 2233434..2234570 - 1137 WP_000115564.1 SAP domain-containing protein -
HZ307_RS11175 2234859..2234951 + 93 WP_001790138.1 hypothetical protein -
HZ307_RS11180 2235656..2236513 - 858 WP_000370924.1 Cof-type HAD-IIB family hydrolase -
HZ307_RS11185 2236581..2237363 - 783 WP_000908176.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T36681 WP_001802298.1 NZ_AP023034:c2232747-2232643 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T36681 NZ_AP023034:c2232747-2232643 [Staphylococcus aureus]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTTATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin


Download         Length: 56 bp

>AT36681 NZ_AP023034:2232530-2232585 [Staphylococcus aureus]
AAAAAGGGCAACACTCGGAAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References