Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprA1-sprA1AS/-
Location 1896875..1897057 Replicon chromosome
Accession NZ_AP023034
Organism Staphylococcus aureus strain TPS3156

Toxin (Protein)


Gene name sprA1 Uniprot ID -
Locus tag HZ307_RS09180 Protein ID WP_001801861.1
Coordinates 1896875..1896970 (+) Length 32 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 1896998..1897057 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HZ307_RS09140 1892535..1893161 + 627 WP_000669046.1 hypothetical protein -
HZ307_RS09145 1893202..1893546 + 345 WP_000627551.1 DUF3969 family protein -
HZ307_RS09150 1893644..1894195 + 552 WP_000414205.1 hypothetical protein -
HZ307_RS09155 1894413..1895054 - 642 WP_000494956.1 ImmA/IrrE family metallo-endopeptidase -
HZ307_RS09160 1895168..1895353 - 186 WP_000809857.1 hypothetical protein -
HZ307_RS09165 1895355..1895531 - 177 WP_000375476.1 hypothetical protein -
HZ307_RS09170 1895542..1895925 - 384 WP_000070811.1 hypothetical protein -
HZ307_RS09175 1896529..1896672 - 144 WP_001549059.1 transposase -
HZ307_RS09180 1896875..1896970 + 96 WP_001801861.1 type I toxin-antitoxin system Fst family toxin PepA1 Toxin
- 1896998..1897057 - 60 - - Antitoxin
HZ307_RS09185 1897093..1897194 + 102 WP_001791893.1 hypothetical protein -
HZ307_RS09190 1897172..1897348 - 177 Protein_1807 transposase -
HZ307_RS09195 1897542..1897919 - 378 WP_001037045.1 DUF1433 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - lukD / hlgA 1870849..1930146 59297


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 32 a.a.        Molecular weight: 3554.32 Da        Isoelectric Point: 10.4449

>T36671 WP_001801861.1 NZ_AP023034:1896875-1896970 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Download         Length: 96 bp

>T36671 NZ_AP023034:1896875-1896970 [Staphylococcus aureus]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin


Download         Length: 60 bp

>AT36671 NZ_AP023034:c1897057-1896998 [Staphylococcus aureus]
ACAACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References