Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/COG4683-HTH_37
Location 5376123..5376828 Replicon chromosome
Accession NZ_AP022871
Organism Phytohabitans suffuscus strain NBRC 105367

Toxin (Protein)


Gene name HigB2 Uniprot ID -
Locus tag Psuf_RS23605 Protein ID WP_173159132.1
Coordinates 5376454..5376828 (-) Length 125 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag Psuf_RS23600 Protein ID WP_173159131.1
Coordinates 5376123..5376461 (-) Length 113 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
Psuf_RS23580 5372349..5372641 + 293 Protein_4713 DUF503 domain-containing protein -
Psuf_RS23585 5372737..5373213 + 477 WP_173159130.1 30S ribosome-binding factor RbfA -
Psuf_RS23590 5373219..5374271 + 1053 WP_173166795.1 bifunctional oligoribonuclease/PAP phosphatase NrnA -
Psuf_RS23595 5374783..5376083 + 1301 Protein_4716 MATE family efflux transporter -
Psuf_RS23600 5376123..5376461 - 339 WP_173159131.1 XRE family transcriptional regulator Antitoxin
Psuf_RS23605 5376454..5376828 - 375 WP_173159132.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
Psuf_RS23610 5376979..5377860 + 882 WP_173159133.1 tRNA pseudouridine(55) synthase TruB -
Psuf_RS23615 5377850..5380840 - 2991 WP_173159134.1 NACHT domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(18-111)

Antitoxin

HigA2-like, helix-turn-helix domain

(39-101)


Sequences

Toxin        


Download         Length: 125 a.a.        Molecular weight: 13876.10 Da        Isoelectric Point: 10.6927

>T36628 WP_173159132.1 NZ_AP022871:c5376828-5376454 [Phytohabitans suffuscus]
MSWSIIVLEPARSWLHSLRRTDRDTLMLVSQAIEALGIEGPALGRPLVDTVKGSRLANLKELRPGSRGAGKVRILFVFDP
LRRAVILVGGDKAGRWRSWYSSAIPMAEAAYGEHLKRMEEQTHE

Download         Length: 375 bp

>T36628 NZ_AP022871:c5376828-5376454 [Phytohabitans suffuscus]
ATGAGTTGGTCGATCATCGTCCTGGAGCCGGCCCGATCCTGGCTCCACTCACTGCGCCGCACCGATCGCGACACCCTCAT
GCTGGTCAGCCAGGCCATCGAGGCGCTCGGCATCGAGGGGCCAGCGCTCGGCCGGCCGCTGGTCGACACGGTCAAGGGCT
CCCGCCTGGCCAATCTCAAGGAGCTGCGCCCCGGATCGCGCGGCGCGGGCAAGGTCCGGATCCTGTTCGTCTTCGACCCG
CTCCGGCGGGCGGTGATCCTCGTCGGTGGCGACAAGGCCGGCCGCTGGCGCAGTTGGTATTCGTCGGCCATCCCGATGGC
CGAAGCGGCATACGGCGAGCATCTGAAACGCATGGAGGAGCAGACGCATGAGTGA

Antitoxin


Download         Length: 113 a.a.        Molecular weight: 12497.97 Da        Isoelectric Point: 5.6954

>AT36628 WP_173159131.1 NZ_AP022871:c5376461-5376123 [Phytohabitans suffuscus]
MSDHLSDHDARSWEDLKDDLAFTEAERAEIDAGARRFVAESRAHRLAEVRRRQQTTQVEVAKAMGVTQARVSRIEKGQLA
RTEVETLAAYVRALGGKLTIVADFGDEQFVLG

Download         Length: 339 bp

>AT36628 NZ_AP022871:c5376461-5376123 [Phytohabitans suffuscus]
ATGAGTGACCACCTGAGCGACCACGATGCCCGGTCCTGGGAGGACCTCAAGGACGATCTCGCCTTCACCGAGGCCGAGCG
GGCCGAGATCGACGCCGGTGCGCGGCGGTTCGTCGCCGAGTCGCGGGCCCACCGGCTGGCGGAGGTGCGCCGCCGGCAGC
AGACGACCCAGGTCGAGGTGGCCAAGGCGATGGGCGTCACCCAGGCCCGGGTGTCCCGCATCGAAAAGGGCCAGCTCGCA
CGCACCGAGGTGGAGACCCTCGCGGCATACGTGCGCGCCCTCGGCGGCAAGCTCACGATCGTCGCCGACTTCGGCGACGA
GCAGTTCGTGCTGGGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References