Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/COG4683-HTH_37
Location 4001740..4002412 Replicon chromosome
Accession NZ_AP022871
Organism Phytohabitans suffuscus strain NBRC 105367

Toxin (Protein)


Gene name HigB2 Uniprot ID -
Locus tag Psuf_RS17370 Protein ID WP_173166536.1
Coordinates 4001740..4002105 (+) Length 122 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag Psuf_RS17375 Protein ID WP_173158210.1
Coordinates 4002092..4002412 (+) Length 107 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
Psuf_RS17350 3997001..3997690 + 690 WP_173158206.1 hypothetical protein -
Psuf_RS17355 3997673..3998830 - 1158 WP_197945926.1 4-hydroxybenzoate 3-monooxygenase -
Psuf_RS17360 3998911..3999477 - 567 WP_173158208.1 hypothetical protein -
Psuf_RS17365 3999505..4001508 - 2004 WP_173158209.1 AAA family ATPase -
Psuf_RS17370 4001740..4002105 + 366 WP_173166536.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
Psuf_RS17375 4002092..4002412 + 321 WP_173158210.1 helix-turn-helix transcriptional regulator Antitoxin
Psuf_RS17380 4002426..4002956 + 531 Protein_3483 helix-turn-helix transcriptional regulator -
Psuf_RS17385 4002965..4003486 + 522 WP_173166538.1 MFS transporter -
Psuf_RS17390 4003514..4004353 + 840 WP_173158211.1 menaquinone biosynthesis protein -
Psuf_RS17395 4004385..4005319 - 935 Protein_3486 hypothetical protein -
Psuf_RS17400 4005323..4006237 - 915 WP_173166540.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(14-105)

Antitoxin

Cro/C1-type helix-turn-helix domain

(42-92)


Sequences

Toxin        


Download         Length: 122 a.a.        Molecular weight: 13665.39 Da        Isoelectric Point: 4.9310

>T36622 WP_173166536.1 NZ_AP022871:4001740-4002105 [Phytohabitans suffuscus]
MTDQVEAFLNGLYAADPDTHRLVNQAILVLERNGPAEGRPLVDSITASQISNMKELRPPSGGRTEIRILFVFDPWRSAVL
LVAGDKSGQWHRWYREAIPEAEQLYATYLKERQGEIGDERG

Download         Length: 366 bp

>T36622 NZ_AP022871:4001740-4002105 [Phytohabitans suffuscus]
ATGACCGACCAGGTGGAGGCGTTTCTAAACGGGCTGTATGCCGCGGATCCTGACACGCACCGGCTGGTCAACCAGGCGAT
CCTCGTCCTGGAGCGCAATGGTCCGGCCGAAGGGCGGCCGCTTGTCGACAGCATCACCGCGTCGCAGATCAGCAACATGA
AGGAGCTTCGGCCGCCGTCGGGCGGCCGCACAGAGATCAGGATTCTCTTCGTCTTCGATCCATGGCGGTCGGCGGTGCTG
CTGGTCGCGGGGGACAAGTCCGGTCAATGGCATCGTTGGTACCGCGAGGCCATTCCGGAGGCGGAGCAGCTCTACGCGAC
ATATCTGAAAGAACGGCAGGGGGAGATTGGCGATGAGCGGGGTTAA

Antitoxin


Download         Length: 107 a.a.        Molecular weight: 11389.92 Da        Isoelectric Point: 8.6814

>AT36622 WP_173158210.1 NZ_AP022871:4002092-4002412 [Phytohabitans suffuscus]
MSGVKRWRDTDHLSRAVETAGGQEAFDAAVGGMLDEARGWRLAELRKRRGMTQDQVASRMGVSVARVSQIEAGAVSTQDV
LGRYIAALGGTLKLIADFGDEQLKVA

Download         Length: 321 bp

>AT36622 NZ_AP022871:4002092-4002412 [Phytohabitans suffuscus]
ATGAGCGGGGTTAAGCGGTGGCGCGACACCGACCACCTGTCGCGGGCTGTGGAAACAGCGGGTGGTCAGGAGGCTTTCGA
CGCCGCCGTAGGCGGGATGCTCGACGAGGCCCGCGGCTGGAGGCTTGCCGAGCTGCGCAAGCGGCGCGGCATGACCCAGG
ACCAGGTGGCCTCCCGCATGGGCGTTTCCGTGGCACGGGTCTCGCAGATCGAGGCGGGTGCCGTCTCCACGCAAGATGTT
CTCGGCAGGTACATCGCCGCGCTCGGTGGCACGTTGAAGCTCATCGCCGACTTCGGCGACGAGCAGCTCAAGGTCGCGTG
A

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References