Detailed information of TA system TA036551

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): higBA (relBE)/HigB-HigA
• Location: 2338526..2339172
• Replicon: chromosome
• Accession: NZ_AP022821
• Organism: Halomonas meridiana strain Slthf1

Toxin (Protein)

• Gene name: higB
• Uniprot ID: -
• Locus tag: HMSLTHF_RS11075
• Protein ID: WP_063744303.1
• Coordinates: 2338526..2338717 (+)
• Length: 64 a.a.

Antitoxin (Protein)

• Gene name: higA
• Uniprot ID: -
• Locus tag: HMSLTHF_RS11080
• Protein ID: WP_058577260.1
• Coordinates: 2338717..2339172 (+)
• Length: 152 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	flank	IS/Tn	-	-	2338080..2338451	371

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, mRNA interferase HigB (1-53)

Antitoxin

• Antitoxin HigA (5-139)

Sequences

Toxin

Protein

• Length: 64 a.a.
• Molecular weight: 7641.02 Da
• Isoelectric Point: 10.1415

>T36551 WP_063744303.1 NZ_AP022821:2338526-2338717 [Halomonas meridiana]
MKAMFPSLDNFKYVDKWWVVDIGGNNLRLIAFIDFEKQRLFTKHLVTHVMYNTLCKKYAQEKR

Nucleotide

• Length: 192 bp

>T36551 NZ_AP022821:2338526-2338717 [Halomonas meridiana]
ATGAAAGCCATGTTTCCAAGCCTAGATAACTTCAAATACGTGGACAAATGGTGGGTGGTTGACATAGGGGGTAATAATCT
GAGGCTTATTGCCTTTATAGACTTTGAAAAACAACGGTTGTTTACCAAGCACCTAGTGACTCACGTCATGTACAACACAC
TGTGCAAAAAATACGCACAGGAGAAGAGATAA

Antitoxin

Protein

• Length: 152 a.a.
• Molecular weight: 17221.41 Da
• Isoelectric Point: 4.2022

>AT36551 WP_058577260.1 NZ_AP022821:2338717-2339172 [Halomonas meridiana]
MNAIAIIQPADKLFKEAPFLVRIHHHAEYEDALALVETLLDEENEDNDFLIERLTDVIEEWEDTAPELSTFNESLSALDG
VDMLKFLMEQNDLGTADLPEIGSKSYVSKVLNRKRELTRRHIEALSARFRVEPALFLADNEWPIGQGEALK

Nucleotide

• Length: 456 bp

>AT36551 NZ_AP022821:2338717-2339172 [Halomonas meridiana]
ATGAACGCAATCGCTATTATCCAACCCGCTGACAAGCTATTTAAAGAAGCGCCCTTCCTCGTGAGAATCCATCATCACGC
CGAGTATGAAGACGCTCTGGCCTTAGTAGAAACGCTGCTAGACGAGGAAAATGAGGATAATGACTTTCTCATTGAGCGGC
TGACCGATGTTATCGAGGAGTGGGAAGACACGGCTCCTGAGCTCTCAACTTTTAACGAATCCCTATCGGCGCTGGATGGC
GTGGATATGCTGAAATTTCTAATGGAGCAGAACGACTTAGGTACTGCCGATCTTCCCGAAATCGGCAGCAAATCTTATGT
CTCAAAAGTGCTTAATCGAAAACGCGAACTGACACGTCGCCATATTGAGGCATTATCAGCCCGCTTTAGGGTCGAACCTG
CCCTATTTTTAGCCGATAATGAATGGCCTATTGGGCAAGGTGAGGCGCTCAAATAA