Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | higBA (relBE)/HigB-HigA |
Location | 1227019..1227743 | Replicon | chromosome |
Accession | NZ_AP022498 | ||
Organism | Enterobacter kobei strain STN0717-53 |
Toxin (Protein)
Gene name | higB | Uniprot ID | A0A7I7DX37 |
Locus tag | JLH17_RS05795 | Protein ID | WP_045268290.1 |
Coordinates | 1227435..1227743 (-) | Length | 103 a.a. |
Antitoxin (Protein)
Gene name | higA | Uniprot ID | A0A7I7DW08 |
Locus tag | JLH17_RS05790 | Protein ID | WP_045268291.1 |
Coordinates | 1227019..1227438 (-) | Length | 140 a.a. |
Genomic Context
Location: 1222200..1222757 (558 bp)
Type: Others
Protein ID: WP_052684026.1
Type: Others
Protein ID: WP_052684026.1
Location: 1222922..1223485 (564 bp)
Type: Others
Protein ID: WP_045268304.1
Type: Others
Protein ID: WP_045268304.1
Location: 1223643..1224029 (387 bp)
Type: Others
Protein ID: WP_045268295.1
Type: Others
Protein ID: WP_045268295.1
Location: 1224254..1224781 (528 bp)
Type: Others
Protein ID: Protein_1122
Type: Others
Protein ID: Protein_1122
Location: 1224781..1225185 (405 bp)
Type: Others
Protein ID: WP_052684025.1
Type: Others
Protein ID: WP_052684025.1
Location: 1228037..1228825 (789 bp)
Type: Others
Protein ID: WP_045268289.1
Type: Others
Protein ID: WP_045268289.1
Location: 1230706..1231485 (780 bp)
Type: Others
Protein ID: WP_014882917.1
Type: Others
Protein ID: WP_014882917.1
Location: 1225654..1226127 (474 bp)
Type: Others
Protein ID: WP_014882896.1
Type: Others
Protein ID: WP_014882896.1
Location: 1226296..1226886 (591 bp)
Type: Others
Protein ID: WP_045268292.1
Type: Others
Protein ID: WP_045268292.1
Location: 1227019..1227438 (420 bp)
Type: Antitoxin
Protein ID: WP_045268291.1
Type: Antitoxin
Protein ID: WP_045268291.1
Location: 1227435..1227743 (309 bp)
Type: Toxin
Protein ID: WP_045268290.1
Type: Toxin
Protein ID: WP_045268290.1
Location: 1228966..1229421 (456 bp)
Type: Others
Protein ID: WP_023332323.1
Type: Others
Protein ID: WP_023332323.1
Location: 1229719..1230600 (882 bp)
Type: Others
Protein ID: Protein_1130
Type: Others
Protein ID: Protein_1130
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Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
JLH17_RS05755 | 1222200..1222757 | + | 558 | WP_052684026.1 | hypothetical protein | - |
JLH17_RS05760 | 1222922..1223485 | + | 564 | WP_045268304.1 | hypothetical protein | - |
JLH17_RS05765 | 1223643..1224029 | + | 387 | WP_045268295.1 | hypothetical protein | - |
JLH17_RS05770 | 1224254..1224781 | + | 528 | Protein_1122 | HNH endonuclease | - |
JLH17_RS05775 | 1224781..1225185 | + | 405 | WP_052684025.1 | SMI1/KNR4 family protein | - |
JLH17_RS05780 | 1225654..1226127 | - | 474 | WP_014882896.1 | GNAT family N-acetyltransferase | - |
JLH17_RS05785 | 1226296..1226886 | - | 591 | WP_045268292.1 | hypothetical protein | - |
JLH17_RS05790 | 1227019..1227438 | - | 420 | WP_045268291.1 | helix-turn-helix domain-containing protein | Antitoxin |
JLH17_RS05795 | 1227435..1227743 | - | 309 | WP_045268290.1 | type II toxin-antitoxin system HigB family toxin | Toxin |
JLH17_RS05800 | 1228037..1228825 | + | 789 | WP_045268289.1 | phosphotransferase | - |
JLH17_RS05805 | 1228966..1229421 | - | 456 | WP_023332323.1 | hypothetical protein | - |
JLH17_RS05810 | 1229719..1230600 | - | 882 | Protein_1130 | LysR family transcriptional regulator | - |
JLH17_RS05815 | 1230706..1231485 | + | 780 | WP_014882917.1 | acetolactate decarboxylase | - |
Associated MGEs
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MGE detail | Similar MGEs | Relative position | MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
No matching records found |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 103 a.a. Molecular weight: 11883.64 Da Isoelectric Point: 8.5216
>T35819 WP_045268290.1 NZ_AP022498:c1227743-1227435 [Enterobacter kobei]
MLAVSRAPFDTATRQFPNHALALDDLYRIQKRSTTRHQTTCESSYLAWLDEISVKMMGIDVGGVHFRVMFFADFERGKIF
IKHISTHAECDKLTDLYRRTKE
MLAVSRAPFDTATRQFPNHALALDDLYRIQKRSTTRHQTTCESSYLAWLDEISVKMMGIDVGGVHFRVMFFADFERGKIF
IKHISTHAECDKLTDLYRRTKE
Download Length: 309 bp
>T35819 NZ_AP022498:c1227743-1227435 [Enterobacter kobei]
ATGCTCGCAGTCTCAAGAGCGCCTTTCGACACAGCGACCAGACAATTTCCCAATCATGCACTCGCTCTGGACGATCTTTA
CCGAATACAAAAAAGGAGCACTACCCGTCACCAGACGACATGCGAAAGCTCTTACCTAGCCTGGCTGGATGAAATTTCAG
TAAAAATGATGGGCATTGATGTGGGTGGAGTACATTTTAGAGTAATGTTTTTTGCTGATTTTGAGCGGGGAAAGATCTTC
ATCAAACACATCAGCACACACGCAGAGTGTGACAAGCTCACGGACCTCTACCGCAGAACGAAAGAATGA
ATGCTCGCAGTCTCAAGAGCGCCTTTCGACACAGCGACCAGACAATTTCCCAATCATGCACTCGCTCTGGACGATCTTTA
CCGAATACAAAAAAGGAGCACTACCCGTCACCAGACGACATGCGAAAGCTCTTACCTAGCCTGGCTGGATGAAATTTCAG
TAAAAATGATGGGCATTGATGTGGGTGGAGTACATTTTAGAGTAATGTTTTTTGCTGATTTTGAGCGGGGAAAGATCTTC
ATCAAACACATCAGCACACACGCAGAGTGTGACAAGCTCACGGACCTCTACCGCAGAACGAAAGAATGA
Antitoxin
Download Length: 140 a.a. Molecular weight: 15502.49 Da Isoelectric Point: 4.5034
>AT35819 WP_045268291.1 NZ_AP022498:c1227438-1227019 [Enterobacter kobei]
MNYAAAIKAANDLTNELPFLGSSPSRQDYEDALTLVEYLIEHDPDSPLVELLTVKIDKYENESAEFAEFNARFASISSGV
ALLRTLMDQYQLTQSDFENEIGKKSLVSRILNGQRTLTLDHMRALAKRFGLPVSAFVGN
MNYAAAIKAANDLTNELPFLGSSPSRQDYEDALTLVEYLIEHDPDSPLVELLTVKIDKYENESAEFAEFNARFASISSGV
ALLRTLMDQYQLTQSDFENEIGKKSLVSRILNGQRTLTLDHMRALAKRFGLPVSAFVGN
Download Length: 420 bp
>AT35819 NZ_AP022498:c1227438-1227019 [Enterobacter kobei]
ATGAATTATGCAGCAGCCATCAAAGCGGCAAATGATCTGACAAACGAGCTCCCTTTCCTGGGATCAAGCCCGTCACGACA
AGATTATGAGGATGCGCTGACACTTGTGGAGTATCTGATTGAGCATGACCCCGATAGCCCGCTGGTAGAATTGCTCACCG
TCAAAATCGATAAATACGAAAACGAGTCTGCGGAGTTTGCAGAATTTAACGCGCGCTTTGCCAGCATTTCATCTGGAGTT
GCACTGCTGAGAACGCTGATGGATCAGTACCAACTCACTCAGAGCGACTTTGAGAATGAGATTGGCAAGAAGTCTTTGGT
GAGTCGGATCCTCAACGGACAGCGCACGTTAACGCTGGATCATATGCGCGCGCTGGCGAAGCGTTTTGGATTGCCAGTGA
GTGCGTTTGTGGGGAATTGA
ATGAATTATGCAGCAGCCATCAAAGCGGCAAATGATCTGACAAACGAGCTCCCTTTCCTGGGATCAAGCCCGTCACGACA
AGATTATGAGGATGCGCTGACACTTGTGGAGTATCTGATTGAGCATGACCCCGATAGCCCGCTGGTAGAATTGCTCACCG
TCAAAATCGATAAATACGAAAACGAGTCTGCGGAGTTTGCAGAATTTAACGCGCGCTTTGCCAGCATTTCATCTGGAGTT
GCACTGCTGAGAACGCTGATGGATCAGTACCAACTCACTCAGAGCGACTTTGAGAATGAGATTGGCAAGAAGTCTTTGGT
GAGTCGGATCCTCAACGGACAGCGCACGTTAACGCTGGATCATATGCGCGCGCTGGCGAAGCGTTTTGGATTGCCAGTGA
GTGCGTTTGTGGGGAATTGA
Structures
Toxin
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Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A7I7DX37 |
Antitoxin
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Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A7I7DW08 |